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Cervical Orthosis Versus no Orthosis Following Multi-level Posterior Cervical Fusion

Not Applicable
Completed
Conditions
Posterior Cervical Spinal Surgery
Myelopathy Cervical
Spinal Stenosis Cervical
Spondylosis, Cervical
Radiculopathy, Cervical
Interventions
Device: No Orthosis
Device: Cervical Orthosis (CO)
Registration Number
NCT04308122
Lead Sponsor
Dr. Christopher Bailey
Brief Summary

Use of cervical orthosis after instrumented posterior cervical spinal surgery is still widely practiced even though modern fusion techniques likely do not require additional stabilization from an external orthosis. This is a single, centre randomized, non-blinded equivalence trial. Patients undergoing multi-level posterior cervical fusion will be randomized to cervical orthosis (CO group) or no orthosis (NO group). Immediately following surgery patients in the CO group will be fitted with a Philadelphia collar prior to being transferred to the recovery room. On the patient ward a physiotherapist will fit the patient with a Cervimax/Aspen/Miami J collar which will be worn at all times for 6 weeks according the standard of care. The NO group will have no specific precautions applied to their neck range of motion. Outcomes will be assessed prior to surgery, on the second day after surgery, and at 2, 4, 6 and 12 weeks after surgery. The primary outcome will be neck pain score on the numerical rating scale (ranging from 0-10 with higher scores indicating more severe pain) during the first 4 weeks after surgery with an equivalence margin of 2.0 points. Secondary outcomes will be neck disability, general health, treatment satisfaction, pain medication use, adverse events, neck range of motion, time meeting discharge status, and compliance in wearing the collar.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
64
Inclusion Criteria
  1. Undergoing multi-level (2- or more level), open, posterior cervical fusion which may extent into the second thoracic vertebrae (C1-T2)
  2. Able to consent to inclusion in the study
  3. 18 years of age and older
Exclusion Criteria
  1. Spinal cord injury
  2. Primary cervical spine infection
  3. Cervical spine tumor
  4. Inability to comprehend patient rated outcome instruments
  5. Substance abuse
  6. Dementia
  7. Psychosis
  8. Previous surgery at same level

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
No Orthosis (NO)No OrthosisNo cervical orthosis will be worn after posterior cervical fusion
Cervical Orthosis (CO)Cervical Orthosis (CO)Cervical orthosis will be worn at all times for 6 weeks according the standard of care after posterior cervical fusion
Primary Outcome Measures
NameTimeMethod
Neck pain intensityThrough study duration to 12 weeks

numerical rating scale, 0 to 10 with higher scores indicating more severe pain

Secondary Outcome Measures
NameTimeMethod
Arm pain intensityThrough study duration to 12 weeks

numerical rating scale, 0 to 10 with higher scores indicating more severe pain

Treatment satisfaction (% of patients satisfied)Through study duration to 12 weeks

Treatment satisfaction will be assessed by the following question: "Are you satisfied with the results of your spine surgery?" using a 5-category scale as follows: 1) extremely satisfied, 2) somewhat satisfied, 3) Neither satisfied nor dissatisfied, 4) somewhat dissatisfied, 5) extremely dissatisfied.

General health SF12Through study duration to 12 weeks

is a generic, multidimensional self-report health questionnaireQuestions are categorized into scales for general health, physical functioning, social functioning, role limitation-physical, role limitation-emotional, mental health, energy/fatigue, pain, comparative health. These are summarized into the SF12-physical component summary score (PCS) and mental component summary score (MCS). Scores range from 0 to 100 with higher scores impling better functioning.

Time to meet discharge status (days)day 2

measured as the number of days it takes to meet all discharge criteria including:

* Ambulating safely and independently as assessed by the physiotherapist

* Pain controlled with oral analgesics

* Minimal wound drainage following drain removal

* For the CO group only: proficient donning and doffing the CO as assessed by physiotherapy/occupation therapy

Pain medication usageThrough study duration to 12 weeks

The total dosage of opioids and NSAID for the hospital length of stay will be calculated. The type of medication used (over the counter, NSAID, muscle relaxant, narcotics, anti-depressant, neuroeleptic and other) will be indicated as not taken, as needed, and daily at week 2, 4, 6, and 12 after surgery.

Compliance with wearing the collar (collar group only)Through study duration to 12 weeks

Patients will be asked they used the collar as prescribed. If not, they will be asked if they wore the collar at all, and if yes for how many hours per day. Compliance will be defined as prescribed, irregular or aborted. Patients will be compliant if they wear the collar for\> 20 hours per day.

Adverse Events rate (%)Through study duration to 12 weeks

The Spinal Adverse Events Severity Grading System (SAVES) form will be used to capture intra-operative, peri-operative, and post-operative adverse events and serious adverse events.

Range of motionThrough study duration to 12 weeks

Change in cobb angle in flexion-extension xrays and a goniometer to measure flexion-extension and rotation

Neck Disability IndexThrough study duration to 12 weeks

NDI is a self-administered questionnaire with 10 questions. Each question is scored from 0 to 5 for a maximum score of 50 and the score converted to a percentage score. The scale ranges from 0 to 100 with a higher score denoting worse disability.

Trial Locations

Locations (1)

London Health Sciences Centre

🇨🇦

London, Ontario, Canada

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