ISRCTN95526224
Completed
未知
In vivo longitudinal evaluation of vertebral bone strength in patients with rheumatoid arthritis treated with alendronate
Kyushu University, Department of Orthopaedic Surgery (Japan)0 sites30 target enrollmentSeptember 10, 2007
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Rheumatoid arthritis
- Sponsor
- Kyushu University, Department of Orthopaedic Surgery (Japan)
- Enrollment
- 30
- Status
- Completed
- Last Updated
- 4 years ago
Overview
Brief Summary
2008 results in https://pubmed.ncbi.nlm.nih.gov/18975334/ (added 10/06/2021)
Investigators
Eligibility Criteria
Inclusion Criteria
- •Female postmenopausal patients with RA who met the American College of Rheumatology diagnostic criteria for RA.
Exclusion Criteria
- •1\. The presence of abnormalities on spinal radiographs such as severe osteophytosis, scoliosis, spinal fusion, fracture deformation
- •2\. Any disease known to affect bone turnover
- •3\. Current or past glucocorticoid therapy comprising greater than 7\.5 mg/day (predonisone equivalent)
- •4\. Current or past use of anabolic steroids, calcitonin, supplemental vitamin D or vitamin K, bisphosphonate
- •5\. Current or past hormone replacement therapy
- •6\. Spinal areal Bone Mineral Density (BMD) T\-score greater than \-1\.0
Outcomes
Primary Outcomes
Not specified
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