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临床试验/ISRCTN95526224
ISRCTN95526224已完成未知

In vivo longitudinal evaluation of vertebral bone strength in patients with rheumatoid arthritis treated with alendronate

Kyushu University, Department of Orthopaedic Surgery (Japan)0 个研究点目标入组 30 人开始时间: 2007年9月10日最近更新:
适应症

试验速览

阶段
未知
状态
已完成
发起方
入组人数
30

研究概览

简要总结

2008 results in https://pubmed.ncbi.nlm.nih.gov/18975334/ (added 10/06/2021)

研究设计

研究类型
Interventional

入排标准

性别
Female

入选标准

  • Female postmenopausal patients with RA who met the American College of Rheumatology diagnostic criteria for RA.

排除标准

  • 1. The presence of abnormalities on spinal radiographs such as severe osteophytosis, scoliosis, spinal fusion, fracture deformation
  • 2. Any disease known to affect bone turnover
  • 3. Current or past glucocorticoid therapy comprising greater than 7.5 mg/day (predonisone equivalent)
  • 4. Current or past use of anabolic steroids, calcitonin, supplemental vitamin D or vitamin K, bisphosphonate
  • 5. Current or past hormone replacement therapy
  • 6. Spinal areal Bone Mineral Density (BMD) T-score greater than -1.0

研究者

发起方
Kyushu University, Department of Orthopaedic Surgery (Japan)

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