CTRI/2024/10/074565尚未招募2/3 期
Comparative evaluation of intraperitoneal instillation of bupivacaine with magnesium sulphate versus bupivacaine with dexmedetomidine for post operative relief after laparoscopic cholecystectomy
LLRM medical College1 个研究点 分布在 1 个国家目标入组 116 人开始时间: 2024年10月10日最近更新:
试验速览
- 阶段
- 2/3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 116
- 试验地点
- 1
- 主要终点
- To evaluate and compare the efficacy and the quality of analgesia.
研究概览
简要总结
This study is prospective randomised study for comparative evaluation of intraperitoneal instillation of bupivacaine with magnesium sulphate versus bupivacaine with dexmedetomidine for post operative relief after laparoscopic cholecystectomy.
Also will be assessing the timing of requiring first dose of rescue analgesic, total dose of rescue analgesia required, hemodynamic changes and complications if any during post operative period.
研究设计
- 研究类型
- Interventional
- 分配方式
- Other
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •ASA Grade 1 And 2 Age 18-65 Yrs Patients Undergoing Elective Laparoscopic Cholecystectomy surgery Patients With Informed Consent.
排除标准
- •Patients With ASA Grade 3 And 4 Known Allergy Or Hypersensitivity To Local Anaesthetic Drug Pregnancy, Patients With Asthma Or Chronic Lung Disease, Patients With Heart Disease, Patients With Renal Failure And Dialysis Patient Refusal.
结局指标
主要结局
To evaluate and compare the efficacy and the quality of analgesia.
时间窗: Postoperatively pain will be assessed at different time intervals for initial 24 hrs
次要结局
- Timing of requiring first dose of rescue analgesic(Patient to be assessed for 24 hours post operatively)
- Total analgesic consumption in 24 hours(Patient to be assessed for 24 hours post operatively)
- Assess hemodynamic changes(Patient to be assessed for 24 hours post operatively at different time intervals)
- Complications if any(Patient to be assessed for 24 hours post operatively)
研究者
Dr Aditi Raj Singh
Lala Lajpat Rai Memorial Medical College Meerut
研究点 (1)
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