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临床试验/NCT03304405
NCT03304405已完成不适用

Influence of Sagittal Imbalance of the Spine on Gait Pattern in Adult Spinal Deformity

The University of Hong Kong1 个研究点 分布在 1 个国家目标入组 15 人开始时间: 2016年6月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
15
试验地点
1
主要终点
Evaluate the effect of sagittal imbalance on the gait cycle using reflective surface markers

研究概览

简要总结

This study intends to investigate the changes in gait pattern in adult spinal deformity (ASD) patients with sagittal imbalance. It will investigate the gait kinematics in patients who have a mismatch of their spinopelvic parameters, and a positive sagittal balance. The investigators hypothesise that patients with abnormal spinopelvic parameters may demonstrate a pathological gait pattern.

详细描述

With an ageing population, ASD presents as a significant health issue with increasing incidence. Most of the earlier literature concentrated on radiographic measurements of the deformity in the coronal plane, and its surgical correction. However, recent publications have demonstrated that sagittal spinopelvic alignment plays a critical role in pain and disability in patients with ASD, and is a primary determinant of health related quality of life measures. There is substantial evidence that restoration of these parameters after spinal reconstructive surgery is correlated with good clinical outcome.

Maintenance of the ideal sagittal alignment allows an individual to maintain an erect posture with minimal energy expenditure. When there is progressive loss of lumbar lordosis, compensatory mechanisms involving the pelvis, hips and knees occur to extend adjacent segments of the kyphotic spine to allow for compensation of anterior translation of the axis of gravity. However, this compensatory mechanism may potentially result in adverse effect. One of the main disabilities in ASD patients with sagittal imbalance is their decreased walking tolerance. The change in the spinal alignment along with these compensatory mechanisms may result in an inefficient gait worsening their walking tolerance.

Few studies in the literature have investigated the changes in gait pattern in patients with sagittal imbalance. Of those, the patient group was heterogeneous, and the only criterion of sagittal imbalance was a positive sagittal vertical axis (SVA), which the investigators now know is not a complete assessment of the sagittal alignment. The investigators propose to study the change in gait pattern in individuals with abnormal spinopelvic parameters, and how this may affect their quality of lives.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

性别
All
接受健康志愿者

入选标准

  • All patients diagnosed with ASD, fulfilling the following radiographic criteria based on whole spine lateral film are eligible for recruitment:
  • SVA bigger than 47mm
  • Pelvic tilt (PT) bigger than 22deg
  • Pelvic incidence (PI) - lumbar lordosis (LL) bigger than 11deg

排除标准

  • If the aetiology of the ASD of the patient is neuromuscular origin
  • other pathologies that may affect their gait such as previous trauma or surgeries to the pelvis or the lower limbs and joint replacements
  • inability to walk without aids for short distances

结局指标

主要结局

Evaluate the effect of sagittal imbalance on the gait cycle using reflective surface markers

时间窗: 1 year

To evaluate the effect of sagittal imbalance on the gait cycle using reflective surface markers

次要结局

  • Investigate the difference in gait kinematics between normal and abnormal sagittal balance using reflective surface markers(1 year)
  • Investigate different muscle recruitment in gait cycles between normal and abnormal sagittal balance using a submaximal graded exercise test(1 year)
  • Investigate the efficiency in gait differences between normal and abnormal sagittal balance using reflective surface markers(1 year)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Dr. Kenny Kwan

Clinical Assistant Professor

The University of Hong Kong

研究点 (1)

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