Dextrose Infusion by Burettes Versus Dextrose Boluses in Prevention of Neonatal Hypoglycemia
Not Applicable
Terminated
- Conditions
- Once a Preterm Developed Hypoglycemia, no More Blood Glucose Was Measured During the Study Period.
- Interventions
- Drug: 10% dextrose
- Registration Number
- NCT01688674
- Lead Sponsor
- Makerere University
- Brief Summary
NULL HYPOTHESIS • There is no difference in the incidence of hypoglycemia among preterms receiving either two hourly 10% dextrose boluses or 10% dextrose infusion by burettes during the 72 hours of admission in Special Care Unit- Mulago Hospital.
ALTERNATE HYPOTHESIS
• Use of two hourly 10% dextrose boluses increases the incidence of hypoglycemia by 30% compared to 10% dextrose infusion by burettes among preterms admitted to Special Care Unit in the first 72 hours of admission.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- TERMINATED
- Sex
- All
- Target Recruitment
- 140
Inclusion Criteria
- SELECTION CRITERIA Inclusion criteria
- Preterms whose care givers/ mothers gave informed consent
- Preterms whose age was < 24 hours of life
- Preterms with birth weight ≥1kg
- Preterms with random blood sugar ≥ 2.6 mmol/l at admission into SCU.
Exclusion Criteria
- Absence of a biological mother or abandoned baby
- Presence of gross congenital abnormalities.
- Very sick (Apgar score ≤ 5 at 5 minutes
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Exclusion Criteria
Not provided
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Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Bolus arm 10% dextrose two hourly dextrose boluses administered via an intravenous cannula infusion 10% dextrose 10% dextrose infusion by burettes
- Primary Outcome Measures
Name Time Method Incidence proportion of hypoglycemia 3months
- Secondary Outcome Measures
Name Time Method survival measured as a proportion 3months
Trial Locations
- Locations (1)
Mulago Hospital
🇺🇬Kampala, Mulago, Uganda