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Clinical Trials/NCT05015062
NCT05015062
Not yet recruiting
Not Applicable

Effectiveness of a Mobile-based HIV Prevention Intervention for Rural and Low-income Population Involving Incentive Policy for Doctors in Liangshan, China: a Randomized Controlled Trial Protocol

Peking University0 sites4,000 target enrollmentJanuary 2023
ConditionsHIV/AIDS

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
HIV/AIDS
Sponsor
Peking University
Enrollment
4000
Primary Endpoint
HIV-related knowledge improvement
Status
Not yet recruiting
Last Updated
3 years ago

Overview

Brief Summary

This study will be carried out in Liangshan Yi Autonomous Prefecture, Sichuan province, China, using a single-blinded randomized controlled trial design to measure the effects of a mobile-based HIV-related information intervention on group HIV/AIDS prevention. Village doctors will be responsible for sending the HIV-related health education information to the participants. The aim of this study is to develop a generalizable, effective, acceptable, and convenient mobile-based information intervention model to improve HIV-related knowledge, attitudes, practices, and health outcomes in poverty-stricken areas in China and measure the impact of incentive policies on the work of village doctors in Liangshan, China.

Registry
clinicaltrials.gov
Start Date
January 2023
End Date
December 2025
Last Updated
3 years ago
Study Type
Interventional
Study Design
Factorial
Sex
All

Investigators

Sponsor
Peking University
Responsible Party
Principal Investigator
Principal Investigator

Yu Sun

Ph.D., Assistant Director, PKU China Center for Health Economic Research (CCHER)

Peking University

Eligibility Criteria

Inclusion Criteria

  • aged 18 years or older
  • has mobile phone with internet service
  • has and use WeChat and TikTok account regularly
  • willing to provide informed consent
  • speak Mandarin Chinese or Yi ethnic group's language

Exclusion Criteria

  • diagnosed with psychiatric disorders
  • diagnosed with severe cognitive impairment
  • diagnosed with severe physical disabilities
  • has already attended or is currently attending another intervention program
  • plan on moving out of Liangshan in the 18-month study period

Outcomes

Primary Outcomes

HIV-related knowledge improvement

Time Frame: 18 months

Result will be obtained by calculating weighted scores for the indicators in the HIV Knowledge Questionnaire 18 (HIV-KQ-18) to represent the participants' and their family members' level of knowledge measured by the baseline and follow-up questionnaires. The HIV-KQ-18 is a self-administered 18-item questionnaire; the possible scores range from 0 to 18, with 0-9 representing low HIV-related knowledge and 10-18 representing high HIV-related knowledge.

Comparison of the effectiveness of different financial compensations

Time Frame: 18 months

The research team will compare the two interventions to determine what type of financial reward, standardized compensation or participant performance-based compensation, is more effective at incentivizing village doctors to deliver and promote the intervention content.

Secondary Outcomes

  • Effectiveness of secondary knowledge transmission: HIV-related knowledge improvement of the participants' family members(18 months)
  • Behavioral changes: condom use(18 months)
  • Behavioral changes: substance use(18 months)
  • Health outcomes: HIV prevalence(18 months)
  • Health outcomes: mental health(18 months)
  • Health outcomes: all-cause mortality(18 months)
  • Social factors: quality of life(18 months)
  • Social factors: stigma towards HIV(18 months)
  • Social factors: perception of social support(18 months)
  • Retention of HIV-related knowledge(18 months)
  • Feasibility: participants' use of social media applications(18 months)
  • Level of engagement(18 months)
  • Study's acceptability and satisfaction(18 months)
  • Cost-effectiveness of the intervention:(18 months)

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