Spinal Anesthesia for Cesarean Delivery is Associated With Decreases in Regional Cerebral Oxygen Saturation as Assessed by Near- Infrared Spectroscopy

Not Applicable

Completed

• Conditions: Cerebral Oxygen Saturation During Spinal Anesthesia for Cesarean Delivery
• Interventions: Other: Spinal Anesthesia with cerebral oxygen saturation monitoring

• Registration Number: NCT01669135
• Lead Sponsor: University of Athens

Brief Summary

The cerebral oxygen saturation is assessed by means of near-infrared spectometry in parturients undergoing cesarean delivery under spinal anesthesia. The investigators hypothesis was that spinal anesthesia does not influence cerebral oxygen saturation.

Detailed Description

Not available

Study Timeline

• Study Start: 2010-12
• Primary Completion: 2012-05
• Status Verified: 2012-08
• Study Completion: 2012-08
• Study First Submitted: 2012-08-08
• Study First Submitted QC: 2012-08-17
• Last Update Submitted: 2012-08-17
• Study First Posted: 2012-08-20
• Last Update Posted: 2012-08-20

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 34

Inclusion Criteria

• Term healthy parturients

Exclusion Criteria

• Body Mass Index > 35
• preeclampsia
• neurological,cardiovascular, respiratory disease

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Spinal Anesthesia with cerebral oxygen saturation monitoring	Spinal Anesthesia with cerebral oxygen saturation monitoring	The cerebral oxygen saturation of the right and left frontal lobe as well as the thigh oxygen saturation are monitored during spinal anesthesia by means of the near-infrared spectroscopy. Hemodynamic variables were recorded at the same time points.

Primary Outcome Measures

Name	Time	Method
cerebral oxygen saturation of the right frontal lobe	Change from the performing of spinal anesthesia untill 1 minute after delivery	Cerebral oxygen saturation is important as it may affect patient's outcome

Secondary Outcome Measures

Name	Time	Method
cerebral oxygen saturation of the left frontal lobe	5, 10, 50 min after spinal,1 minute after delivery	Cerebral oxygen saturation is important for patient's outcome
Thigh oxygen saturation	5, 10, 50 min after spinal, 1 minute after delivery	Thigh oxygen saturation may reflect blood redistribution due to spinal block
Arterial Oxygenation	5, 10, 50 min after spinal, 1 minute after delivery	Changes in arterial oxygenation may reflect blood redistribution due to spinal block

Trial Locations

Locations (1)

Department of Anesthesiology, Aretaieio Hospital; 🇬🇷 Athens, Greece