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Clinical Trials/NCT03142373
NCT03142373
Completed
N/A

Variations of Heart Rate Variability and Skin Conductance Reveal the Influence of CV4 and Rib Raising Osteopathic Techniques on the Autonomic Nervous System: a Randomized Controlled Trial

Fondazione Don Carlo Gnocchi Onlus0 sites48 target enrollmentJune 2010

Overview

Phase
N/A
Intervention
Not specified
Conditions
Autonomic Nervous System Disease
Sponsor
Fondazione Don Carlo Gnocchi Onlus
Enrollment
48
Primary Endpoint
Heart Rate Variability
Status
Completed
Last Updated
7 years ago

Overview

Brief Summary

Background. Heart rate variability (HRV) and skin conductance (SC) highlight autonomic activity and the balance of autonomic nervous system (ANS) which regulates involuntary physiological functions. The modulation of ANS tonic activity is a target of osteopathic manipulative treatment (OMT). The main aim of the present study was to verify whether CV4 and RR osteopathic techniques influence ANS activity.

Trial design. A randomized-controlled clinical trial was performed from June 2010 to January 2011.

Methods. 32 healthy adults were selected. At enrollment, all healthy subjects were randomized in three groups: CV4 group (CV4 technique), Rib Raising group (RR technique), and Placebo group (PL technique). HRV and SC was recorded during the session respectively with heart rate monitor Polar S810i and with Onda Scanner Domiana (OSD-Microsale model). All data analysis was performed using SPSS statistical software and the significance level set at p≤0.05.

Registry
clinicaltrials.gov
Start Date
June 2010
End Date
January 2011
Last Updated
7 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Chiara Arienti

Dr

Fondazione Don Carlo Gnocchi Onlus

Eligibility Criteria

Inclusion Criteria

  • healthy subjects
  • between 18-65 years old
  • both gender

Exclusion Criteria

  • pregnancy
  • menstrual flow during the session
  • chronic pain
  • chronic drug treatment
  • presence of skin, cardiovascular, psychiatric and neurological diseases
  • medical history of surgical interventions
  • OMT in the previous 3 months

Outcomes

Primary Outcomes

Heart Rate Variability

Time Frame: 1200 seconds

HRV was measured using a heart rate monitor Polar S810i frequency meter

Secondary Outcomes

  • Skin Conductance(1200 seconds)

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