A Clinical Study to compare the Efficacy and Safety of Marham-e-DÄd with Terbinafine in the Management of QÅ«bÄ (Ringworm)

Phase 2

Not yet recruiting

Lead Sponsor: National Research Institute of Unani Medicine for Skin Disorders

Brief Summary: -The prevalence rate of *QÅ«bÄ*(Ringworm) has been found to be 20-25% worldwide.

-It is more prevalent in tropical and subtropical countries like India where the heat and humidity is high throughout the year. â€“

*-QÅ«bÄ* (Ringworm) also has many ill impact on the patientâ€™s quality of life.

-In conventional medicine, some antifungal drugs are used in the treatment of Ringworm, which are becoming resistant to the organism and also have certain adverse effects with antifungal drugs are erythema, itching, dryness, irritation nausea, hepatotoxity, abdominal pain, headache, rashes, hypokalemia and oligozoospermia etc.

-Hence, there is need to search more effective and safe drugs in management of *QÅ«bÄ* (Ringworm).keeping this in view, a unani formulation *Marham-e- DÄd* has been selected to evaluate its efficacy and safety in the management of *QÅ«bÄ* (ringworm)

Recruitment & Eligibility

Inclusion Criteria

Circumscribed lesions having any of the following signs and symptoms on body: .Presence of pruritus and burning .Presence of scales_ .Presence of central clearing .Erythematous papules b) Participants with positive mycology (KOH positive).
c)| Participants of either sex in age group of 19-60 years.

Exclusion Criteria

a) Co-morbid conditions of the participants b) Pregnant or Lactating Women c) Significant Pulmonary/Cardiovascular/Hepato-renal Dysfunction d) Known cases of Immuno-compromised states (HIV/ AIDS, etc.)/Malignancies Participants not willing to attend treatment schedule regularly e) History of hypersensitivity to Itraconazole and Terbinafine.
F) Patient having diabetic.
g) Participants using the following medications: .
Systemic antifungal within 15 days of baseline visit.
Systemic corticosteroids within 15 days of baseline visit.

Primary Outcome Measures

Name	Time	Method
Total Signs and Symptoms Score(TSSS)	42 days

Secondary Outcome Measures

Name	Time	Method
1.Conversion to Negative Mycology	2.Systemic Safety Assesssment

Locations (1): National Research Institute of Unani Medicine for Skin Disorders
🇮🇳
Hyderabad, TELANGANA, India
National Research Institute of Unani Medicine for Skin Disorders
🇮🇳Hyderabad, TELANGANA, India
Anam Farah Sayyed Nisar
Principal investigator
8055669281
anamsyd1996@gmail.com