RBR-3kzp25
Active, Not Recruiting
N/A
Evaluation of the effectiveness of two preventive schemes with amoxicillin for tooth extractions in rheumatoid arthritis patients treated with tumor necrosis factor-alpha inhibitors(anti-TNF-?) and methotrexate
niversidade Federal do Ceará0 sitesJuly 17, 2015
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- niversidade Federal do Ceará
- Status
- Active, Not Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Healthy volunteers and subjects with rheumatoid arthritis who make use of inhibitors of TNF\-alpha and methotrexate.Participants with aged 18 to 75 years.
- •Patients that signed the IC (Informed Consent)and requiring simple extractions, exhibiting in blood tests (INR\- international normalized ratio less than 2\.5 platelet count above the 30\.000; Count leukocytes above the 2\.000 per mm³ and fasting glucose lower than 126 mg/dL). This study aims to enroll about 72 patients.
Exclusion Criteria
- •Patients that used antibiotics in the last 15 days. Patients allergic to Amoxicillin (experimental group).Patients with dental infection(periodontal abscess or periapical abscess).Patients with pre\-existing infection. Patients that used additional immunosuppressive medication and patients who not attended the scheduled follow and/or do not follow the instructions of this study.
Outcomes
Primary Outcomes
Not specified
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