NCT02117375Unknown不适用
EMISEP : Early Spinal Cord Lesions and Late Disability in Relapsing Remitting Multiple Sclerosis Patients
Rennes University Hospital1 个研究点 分布在 1 个国家目标入组 115 人开始时间: 2014年1月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 115
- 试验地点
- 1
- 主要终点
- Progressive neurological disability
研究概览
简要总结
The purpose of this study is to evaluate the prognostic value of early focal lesions and early diffuse lesions on ambulatory disability progression within 5 years after clinical onset.
详细描述
Prospective, multicentric study
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients with multiple sclerosis:
- •Inclusion Criteria:
- •Relapsing Remitting Multiple Sclerosis patients (Mac Donald 2010 criteria)
- •First clinical event < 1 year
- •Brain MRI > 9 lesions or/and spinal cord attack with focal lesion on spinal cord MRI
- •Score Expended Disability Status Scale < 3
- •Age between 18 and 40 years
排除标准
- •Multiple Sclerosis progressive
- •Patients treated with immunosuppressive therapy
- •Pregnancy
- •Healthy volunteers:
- •Inclusion Criteria:
- •Age between 18 and 40 years
- •Exclusion Criteria:
结局指标
主要结局
Progressive neurological disability
时间窗: 5 years
Measurement by Expended Disability Status Scale
次要结局
- Progressive ambulatory disability(5 years)
- Progressive disability in the upper limbs(5 years)
- Progressive urinary disability(5 years)
- Progressive difficulty walking(5 years)
研究者
研究点 (1)
Loading locations...
相似试验
招募中
不适用
Assessment of the Effects of Early Proprioceptive Stimulations in Patients With Spinal Cord InjurySpinal Cord InjuriesNCT05094752Assistance Publique - Hôpitaux de Paris40
已完成
不适用
Early FES Cycling in Acute Spinal Cord Injury for Neuromuscular Preservation and NeurorecoveryAcute Spinal Cord InjuryNCT05255679University of Alberta35
尚未招募
不适用
Prognostication of Recovery in Early Disorders of Consciousness StudyDisorders of Consciousness Due to Severe Brain InjuryNCT04692922Massachusetts General Hospital50
Unknown
不适用
Characterization of Cortical Injury in Early MS Patients: a 7T MRI StudyMultiple Sclerosis (MS)NCT03624296Assistance Publique Hopitaux De Marseille30
招募中
不适用
The Prognostic Impact of Symptoms and Lesion Depth in Partial Removal of Carious TissueDeep CariesPulpitis ReversiblePulp HyperemiaNCT05816525University of Helsinki100