The Clinical Difference Between the Nonfatal Coronavirus Disease 2019 (COVID-19) Patients and the Fatal Cases With Severe COVID-19
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 100
- 试验地点
- 2
- 主要终点
- NK cell
研究概览
简要总结
To investigate the difference of the difference between the nonfatal Coronavirus Disease 2019 (COVID-19) Patients and the fatal Patients .The cross sectional study was undertaken to compare the clinical information (laboratory and radiologic characteristics)of nonfatal participants and fatal cases. The investigators wish figure out the clinical character of the fatal participants. The result may help the physician to find the fatal patients with COVID-19 more easily. The fatal patients with COVID-19 could be treated early.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 20 Years 至 100 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •The patients with Coronavirus Disease 2019
- •Positive result on real-time reverse-transcriptase-polymerase-chain-reaction
- •Positive result on chest computed tomography
排除标准
- 未提供
结局指标
主要结局
NK cell
时间窗: 2 month
natural killer cell(counts/L)
IL-6
时间窗: 2 month
interleukin-6(mg/L)
LDH
时间窗: 2 month
lactate dehydrogenase ( U/L)
CK
时间窗: 2 month
creatine kinase (U/L)
PT
时间窗: 2 month
prothrombin time(second)
AST
时间窗: 2 month
aspartate aminotransferase(U/L)
CRP
时间窗: 2 month
the level of C-reactive protein (mg/uL)
PCT
时间窗: 2 month
procalcitonin（ng/ml）
d-dimer
时间窗: 2 month
d-dimer（mg/L）
PLT
时间窗: 2 month
the counting of Platelets（(counts/L)）
Lymphocyte cell
时间窗: 2 month
the counting of Lymphocyte(counts/L)
ALT
时间窗: 2 month
alanine aminotransferase(U/L)
次要结局
- the clinical difference of radiologic characteristics between the fatal patients with COVID -19 and the non fatal cases(2 months)
研究者
Zhang Jianheng
Principal Investigator
The First Affiliated Hospital of Guangzhou Medical University