MedPath

Virtual Physical Activity Seated Exercise - Phase 2

Not Applicable
Recruiting
Conditions
Stroke Hemorrhagic
Stroke, Ischemic
Stroke
Chronic Stroke
Interventions
Other: Virtual Physical Activity Seated Exercises (V-PASE)
Registration Number
NCT05724823
Lead Sponsor
University of British Columbia
Brief Summary

This study will determine the acceptability of delivering seated exercises online and if seated exercises can improve balance, mobility, quality of life, and cardiometabolic health in those living with a stroke related mobility impairment.

Participants will be allocated to either a 10-week seated exercise program or a delayed 2-week Boot Camp program. All seated exercises sessions and assessments will be conducted virtually.

Detailed Description

The study will be a virtual 10-week multi-site, assessor-blinded, randomized controlled trial with an embedded qualitative component. The study will be conducted in real time using secure videoconferencing software (Zoom). Participants will be randomized 1:1 to a 10-week Seated Exercise group or a delayed 2-week Seated Exercise Group (Boot Camp). Seated exercise sessions will be delivered and supervised by a trained instructor.

Participants will use their own computer, laptop, or tablet for the zoom sessions. No Zoom sessions will be recorded. Caregivers will be invited to attend each exercise session to provide support and assistance but are not obliged to attend. A caregiver, friend, or family member will be required for each assessment to participate in the study.

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
100
Inclusion Criteria

Participants must meet the following inclusion criteria:

  • Adult (as defined by Province)
  • Chronic stroke (more than 6 months post-stroke)
  • Ability to stand up from a chair
  • Mobility impairment of lower extremity (requires a walking aid, with or without close supervision)
  • Able to safely engage in exercise and tolerate 60 minutes of exercises
  • Able to communicate in English
  • Have access to a tablet, computer, or laptop with internet and email access
Exclusion Criteria

Participants will be excluded if they meet any of the following criteria:

  • Participating in formal exercise or rehabilitation activities
  • Participating in > 30 minutes/day of physical activity (moderate intensity)
  • Participating in another study that may affect outcomes to this study
  • Severe loss of vision, hearing, speech (including aphasia) or cognition that would preclude use of a computer/tablet and communication over videoconference software
  • A serious comorbid condition (eg., amputation, Parkinson's disease, active cancer)
  • Clinically diagnosed with acute/chronic illness or other condition which has known physical activity contraindications or limits their ability to complete each experimental condition (i.e., chronic low back pain aggravated by prolonged sitting)

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
10-week groupVirtual Physical Activity Seated Exercises (V-PASE)Will receive a 10-week seated exercise program, occurring 3 times per week. Sessions will be 60 minutes in duration.
Primary Outcome Measures
NameTimeMethod
30 Second Sit-to-StandImmediately post-intervention (following 10-week trial)

Assessment of balance and lower extremity strength.

Secondary Outcome Measures
NameTimeMethod
Glucose (HbA1c)Immediately post-intervention, and retention (2-months post-intervention)

Blood samples will be collected following a 12-hour over-night fast

Stroke Impact ScaleImmediately post-intervention, and retention (2-months post-intervention)

A self-reported measure of stroke-related disability. There are 8 domains with each item rated using a 5-point Likert scale, where lower scores mean greater difficulty to complete the item.

Fatigue Severity ScaleImmediately post-intervention, and retention (2-months post-intervention)

Questionnaire assessing the impact of fatigue on daily tasks and activities. There are 9 questions, each scored from 1 to 7 (1 = strongly disagree; 7 = strong agreement).

Montreal Cognitive Assessment scale (MoCA-BLIND)Immediately post-intervention, and retention (2-months post-intervention)

The MoCA-BLIND assess six different cognitive domains (excludes visual stimulus) over the phone: memory, attention, language, abstraction, delayed recall, and orientation. The MoCA-BLIND is scored from 0-22 (22 = no cognitive impairments).

Activities-Specific Balance Confidence (ABC)Immediately post-intervention, and retention (2-months post-intervention)

The ABC scale is a 16-item questionnaire where a participant rates their confidence in performing activities from 0% to 100% (higher percentages indicate greater self-efficacy).

Timed Up and GoImmediately post-intervention, and retention (2-months post-intervention)

Participants stand up from a chair, walk 3 metres, turn around and then sit back down. The TUG assesses balance, mobility and turning ability

Tandem StanceImmediately post-intervention, and retention (2-months post-intervention)

Measures balance in standing as reported in the Short Physical Performance Battery Protocol

Modified Telehealth Fugl-MeyerImmediately post-intervention, and retention (2-months post-intervention)

The modified virtual Fugl-Meyer assess lower extremity impairments in those with stroke

Quality of Life (EQ-5D-5L)Immediately post-intervention, and retention (2-months post-intervention)

The EQ-5D-5L assess self-care, mobility, depression/anxiety, pain, and usual activities. Each is scored with 5 levels (1=no problems, 5=major problems). Overall health on the day is scored from 0% (worst health) to 100% (best health).

Patient Health Questionnaire-4 (PHQ-4)Immediately post-intervention, and retention (2-months post-intervention)

The PHQ-4 focuses on depression and anxiety. Questions are scored from 0 to 3 (0=not at all; 3 = Nearly every day).

Lipid ProfilesImmediately post-intervention, and retention (2-months post-intervention)

Blood samples will be collected following a 12-hour over-night fast

Fasting GlucoseImmediately post-intervention, and retention (2-months post-intervention)

Blood samples will be collected following a 12-hour over-night fast

30 Second Sit-to-StandRetention (2-months post-intervention)

Assessment of balance and lower extremity strength.

Trial Locations

Locations (5)

University of Manitoba

🇨🇦

Winnipeg, Manitoba, Canada

GF Strong Rehabilitation Centre

🇨🇦

Vancouver, British Columbia, Canada

Nova Scotia Health

🇨🇦

Halifax, Nova Scotia, Canada

Western University

🇨🇦

London, Ontario, Canada

University of Saskatchewan

🇨🇦

Saskatoon, Saskatchewan, Canada

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