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Investigating the efficacy of insert nanofibers containing Vancomycin and Amikacin in patients with infectious keratitis

Not Applicable
Recruiting
Conditions
Corneal ulcer.
Corneal ulcer
H16.0
Registration Number
IRCT20130812014333N216
Lead Sponsor
Kermanshah University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
12
Inclusion Criteria

Age above 18 years
Bacterial corneal ulcer with high clinical suspicion
Wound size greater than 2 mm
BCVA greater than 200/20 in the uninvolved eye

Exclusion Criteria

Patients with uncontrolled diabetes
Corneal perforation or its imminent
Symptoms of inflammation in both eyes
History of glaucoma shunt or filtering surgery
Pregnant or lactating women
History of corneal surgery due to refractive errors

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Reducing the healing time of corneal wounds. Timepoint: every 2 hours on days 3 to 6, every 2 hours when waking up on days 7 to 9, every 6 hours on day 9 and continue treatment until the wound heals. Method of measurement: Based on slit lamp examination with corneal fluorescein staining.
Secondary Outcome Measures
NameTimeMethod
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