The effects of biofeedback therapy on the brain pattern activity and pelvic floor motin of the patients with chronic constipation due to paradoxical Puborectalis contraction syndrome
Not Applicable
- Conditions
- Condition 1: Chronic constipation and dyssynergic defecation. Condition 2: Chronic constipation and dyssynergic defecation.Disorder of muscle, unspecifiedOther biomechanical lesions
- Registration Number
- IRCT2015050320011N2
- Lead Sponsor
- Iran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
The patients, who have two or more symptoms of the diagnostic criteria for functional constipation in more than 1/4 of bowel movements, if the diagnosis of paradoxical contraction of the puborectalis muscle during straining is established by digital rectal examination, can participate in this study. Patients are excluded from the study if they have previous anorectal surgery, anorectal tumors or structural anorectal disorders, which need operation intervention. Other exclusion criteria are significant cardiovascular, respiratory, neurologic, psychiatric illnesses, sever psychological problems or endocrine and metabolic diseases that can cause constipation
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pattern of brain activity. Timepoint: before treatment and after its completion (3 months). Method of measurement: by fMRI.
- Secondary Outcome Measures
Name Time Method Muscle function(paradox index& perinal index). Timepoint: before beginning and after period of treatment(3 mounths). Method of measurement: by dynamic pelvic MRI.;Muscle function(paradox index& perinal index). Timepoint: before beginning and after period of treatment. Method of measurement: dynamic pelvic MRI.;The quality of life. Timepoint: before beginning and after period of treatment. Method of measurement: Sf-36 Questionnaire.;Severity of depression. Timepoint: before beginning and after period of treatment. Method of measurement: BDI-II Questionnaire.