A Randomized Controlled Study of Phacoemulsification by the Enlarged Internal Incision and the Regular 2.2mm Incision
概览
- 阶段
- 不适用
- 干预措施
- 未指定
- 疾病 / 适应症
- Cataract
- 发起方
- Zhongshan Ophthalmic Center, Sun Yat-sen University
- 入组人数
- 294
- 试验地点
- 1
- 主要终点
- descemet membrane detachment(DMD)
- 最后更新
- 6年前
概览
简要总结
Objective and Principle: To evaluate whether enlarging the incision can reduce corneal complications associated with phacoemulsification with regular 2.2 mm incision.
The aim of this study: To evaluate whether the technique of enlarging internal incision could reduce the incidence of descemet membrane detachment after 2.2 mm incision phacoemulsification.
Secondary outcome: To evaluate whether the technique of enlarged internal incision can reduce other corneal complications such as corneal edema and astigmatism after 2.2 mm incision phacoemulsification.
Study Design: A prospective randomized controlled study
研究者
入排标准
入选标准
- •Age-related cataract patients
- •Age from 65 to 90
- •The diameter of pupil after mydriasis is more than 6 mm
- •LOCS III nuclear grade ≥4
- •Corneal endothelial cell count \> 1500 cells/mm2
- •Phacoemulsification and intraocular lens implantation are planned
- •Agree to participate in this study and sign informed consent
排除标准
- •History of ocular trauma
- •Anterior segment lesions (exfoliation syndrome, suspension ligament injury or relaxation, corneal and iris lesions, glaucoma)
- •Other ocular diseases that impair visual function, such as optic neuropathy, uveitis and ocular tumors
- •History of Ophthalmic Surgery
- •Intraoperative and Postoperative Complications
结局指标
主要结局
descemet membrane detachment(DMD)
时间窗: postoperative 1 week
DMD at the incision observed by anterior segment optical coherence tomography