Comparison of Two Pharmacological Treatments of Pedophilia
- Registration Number
- NCT00601276
- Lead Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
- Brief Summary
Sexual abuse committed on children is a major public health problem because of its frequency and its severe consequences on the mental health of victims.
Objective: to compare the therapeutic efficacy of cyproterone acetate (CPA) and leuprolide, with the hypothesis that leuprolide will be more effective.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- TERMINATED
- Sex
- Male
- Target Recruitment
- 48
Inclusion Criteria
- clinical diagnosis of pedophilia
- high frequency of sexual urges and deviant behavior as demonstrated by a score equal to 8 on the scale of Rösler & Witztum (Rösler & Witztum, 1998) ;
- age: 18-60 years
- informed consent
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Exclusion Criteria
- IQ<70
- schizophrenia, schizoaffective disorder, or delusional disorder
- already receiving one of the tested drugs
- contraindication for one of the tested drugs
- no current or planned incarceration
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Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description 1 leuprorelin - 2 Cyproterone acetate -
- Primary Outcome Measures
Name Time Method Questionnaire on sexual behavior prospective
- Secondary Outcome Measures
Name Time Method Recidivism Prospective
Trial Locations
- Locations (4)
Federation d'Endocrinologie, Hopital NeuroCardiologique
🇫🇷Bron, France
Centre MédicoPsychologique CMPG21, EPS Perray Vaucluse
🇫🇷Paris, France
Service de Psychiatrie, Hopital Foch
🇫🇷Suresnes, France
SMPR, Hopital Paul Guiraud
🇫🇷Villejuif, France