se of botulinum toxin-A for musculoskeletal pain in patients with whiplash associated disorders

Completed

• Conditions: Whiplash cervical injuries; Injury, Occupational Diseases, Poisoning; Injuries to the neck

• Registration Number: ISRCTN68653575
• Lead Sponsor: Povisa Medical Center (Povisa Centro Medico) (Spain)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2004-02-02
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 160

Inclusion Criteria

1. Patients with grade II Whiplash Associated Disorders (WAD) of Quebec Task Force (QTF)-WAD
2. Neck pain secondary to cervical whiplash injury with musculoskeletal signs of greater than three months
3. Aged greater than 18 years
4. Lack of response to conventional physical and medical therapy

Musculoskeletal signs:
1. Palpable band, spot tenderness, and jump sign in cervical muscles or restricted range of motion in cervical spine
2. Demonstrated precipitation of neck pain with external pressure over the occipital or cervical region on affected side
3. Myofascial pain of cervical muscles
4. Experienced pain on maneuver of stretching
5. Trigger point with associated referred pain

Exclusion Criteria

1. Serious somatic or psychiatric illness
2. Anticoagulation therapy
3. Myasthenia gravis
4. Pregnancy or breast-feeding
5. Abnormal anatomy
6. Rheumatoid disease or radiculopathy
7. Need for regular analgesic for severe pain

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
ot provided at time of registration

Secondary Outcome Measures

Name	Time	Method
ot provided at time of registration