The clinical effect of compound Syndrome Differentiation with periodontal nonsurgical treatment on the Chronic Periodontitis
Phase 1
- Conditions
- Chronic periodontitis
- Registration Number
- ITMCTR2200006841
- Lead Sponsor
- Beijing Hospital of Integrated Traditional Chinese and Western Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
1, Age from 18 to 65.
2, Patients got chronic periodontitis which according to periodontal classification in 1999.
3, Remind 16 teeth expect the third molar.
4, At last 2 sites PD=5 mm, CAL=2 mm, in different quardent.
5, CBCT show bone loss.
Exclusion Criteria
1, Serious organ dysfunction.
2, Serious infectious diseases.
3, Mental illness or consciousness disorder.
4, Patients got periodontal treatment in last 6 months, took antibiotic, immunomodulator, glucocorticoid or sex hormone in last 3 months.
5, Oral therapy contraindication.
6, Allergy to our study's medicines.
7, Women in pergnancy or lactation period.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Probing depth;Bleeding index;Point table of Syndrome of traditional Chinese medical;
- Secondary Outcome Measures
Name Time Method Reture visit period;TNF-a;Porphyromonas gingivalis;Alveolar bone loss;IL-1ß;IL-1;IL-6;Plaque index;