Role of Oral Glutathione in Skin Whitening

Phase 1

Completed

• Conditions: Skin Whitening
• Interventions: Drug: glutathione; Drug: placebo

• Registration Number: NCT01016080
• Lead Sponsor: Chulalongkorn University

Brief Summary

Oral and intravenous glutathione have been used widely to whiten the skin. The investigators tested this hypothesis by giving oral glutathione for 4 weeks to medical students.

Detailed Description

Not available

Study Timeline

• Study Start: 2009-02
• Primary Completion: 2009-05
• Study Completion: 2009-06
• Status Verified: 2009-11
• Study First Submitted: 2009-11-17
• Study First Submitted QC: 2009-11-17
• Last Update Submitted: 2009-11-17
• Study First Posted: 2009-11-18
• Last Update Posted: 2009-11-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• Healthy medical students

Exclusion Criteria

• history of skin cancer, especially melanoma
• consumption of any preparations containing glutathione within 1 month of enrollment
• pigmentary disorders or any dermatoses

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
oral glutathione	glutathione	glutathione, 500 mg, taken orally twice daily
placebo capsules	placebo	identical-appearing placebo capsules

Primary Outcome Measures

Name	Time	Method
Skin melanin index	4 weeks

Trial Locations

Locations (1)

King Chulalongkorn Memorial Hospital; 🇹🇭 Bangkok, Thailand