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临床试验/CTRI/2020/02/023093
CTRI/2020/02/023093已完成不适用

A double blind randomized study to evaluate and compare the anaesthetic efficacy of 0.75% Ropivacaine and 0.5% Bupivacaine on the perioperative regional analgesia in impacted mandibular third molar surgery

Nisha Mishra1 个研究点 分布在 1 个国家目标入组 50 人开始时间: 2020年5月2日最近更新:

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
50
试验地点
1
主要终点
Onset of Local Anaesthesthetic solution

研究概览

简要总结

The results obtained from this study revealed interesting applications in both clinical and future research on the topic. This study summarizes the unbiased direct comparison of 0.75% ropivacaine and 0.5% bupivacaine. From the results and discussion, this study states that ropivacaine provides a successful and higher rate of local conduction anaesthesia than bupivacaine local anaesthetic solution by providing- the faster onset of anaesthesia, greater depth of anaesthesia, greater duration of anaesthesia, lesser intraoperative pain and lesser intraoperative bleeding. In a comparison of the use of 0.75% ropivacaine and 0.5% bupivacaine local anaesthetic solutions in healthy patients, it could be hypothetically stated that 0.5% bupivacaine could result in mild cardiovascular problems.

Hence to conclude the following results of our study, the magnitude of perioperative pain reduction during the surgery of the lower wisdom tooth is comprehended through the local long-lasting anaesthetic 0.75% ropivacaine, over 2 mL 0.5% bupivacaine. Ropivacaine is better than bupivacaine in the management of pain with no such cardiovascular problems and can be used in regular dental practice.

研究设计

研究类型
Interventional
分配方式
Coin toss, Lottery, toss of dice, shuffling cards etc
盲法
Participant and Investigator Blinded

入排标准

年龄范围
18.00 Year(s) 至 50.00 Year(s)(—)
性别
All

入选标准

  • Impacted Mandibular 3rd molar.

排除标准

  • Allergic to any of the local anaesthetic solution Pregnant Women.

结局指标

主要结局

Onset of Local Anaesthesthetic solution

时间窗: 15 minutes

次要结局

  • Duration of Local Anaesthetic solution(1 hour)

研究者

发起方
Nisha Mishra
申办方类型
Other [self]

研究点 (1)

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