A study to compare the numbness effect of 0.75% ropivacaine and 0.5% bupivacaine in surgical removal of wisdom tooth of lower jaw

Completed

• Conditions: Congenital malformation, unspecified,

• Registration Number: CTRI/2020/02/023093
• Lead Sponsor: Nisha Mishra

Brief Summary

The results obtained from this study revealed interesting applications in both clinical and future research on the topic. This study summarizes the unbiased direct comparison of 0.75% ropivacaine and 0.5% bupivacaine. From the results and discussion, this study states that ropivacaine provides a successful and higher rate of local conduction anaesthesia than bupivacaine local anaesthetic solution by providing- the faster onset of anaesthesia, greater depth of anaesthesia, greater duration of anaesthesia, lesser intraoperative pain and lesser intraoperative bleeding. In a comparison of the use of 0.75% ropivacaine and 0.5% bupivacaine local anaesthetic solutions in healthy patients, it could be hypothetically stated that 0.5% bupivacaine could result in mild cardiovascular problems.

Hence to conclude the following results of our study, the magnitude of perioperative pain reduction during the surgery of the lower wisdom tooth is comprehended through the local long-lasting anaesthetic 0.75% ropivacaine, over 2 mL 0.5% bupivacaine. Ropivacaine is better than bupivacaine in the management of pain with no such cardiovascular problems and can be used in regular dental practice.

Detailed Description

Not available

Study Timeline

• Study Start: 2020-05-02
• Study Completion: 2021-10-14
• Last Update Posted: 2022-04-02

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Impacted Mandibular 3rd molar.

Exclusion Criteria

Allergic to any of the local anaesthetic solution Pregnant Women.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Onset of Local Anaesthesthetic solution	15 minutes

Secondary Outcome Measures

Name	Time	Method
Duration of Local Anaesthetic solution	1 hour

Trial Locations

Locations (1)

Peoples Dental Academy; 🇮🇳 Bhopal, MADHYA PRADESH, India

Peoples Dental Academy

🇮🇳Bhopal, MADHYA PRADESH, India

Nisha Mishra

Principal investigator

9009013215

nishamishra838@gmail.com