The Swinburne Multivitamin Study: Effects of vitamin and herbal supplementation on cognition, brain electrical activity and cardiovascular measures in older adults

Not Applicable

Completed

• Conditions: Cognitive performance; Cardiovascular function; Brain function; Blood markers of general wellbeing; Mental Health - Studies of normal psychology, cognitive function and behaviour; Cardiovascular - Normal development and function of the cardiovascular system; Neurological - Studies of the normal brain and nervous system

• Registration Number: ACTRN12608000117314
• Lead Sponsor: Dr Andrew Pipingas

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2008-03-04
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

Males and females aged 50-70 years.

Exclusion Criteria

Smoking; current supplementation with multivitamins; history of psychiatric disorder, neurological disease, diabetes or food intolerance/allergy

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Percentage accuracy and response time on computerised cognitive tests. Computer tasks include Response Time, Choice Response Time, Recognition Memory, Stroop Task, Spatial Working Memory, Contextual Memory, and Delayed Recognition Memory.[before and after 16 weeks of supplementation];patterns of brain electrical activity using the steady state visual evoked potential technique[before and after 16 weeks of supplementation];Blood pressure and augmentation index as measured by the Sphygmocor pulse wave analysis system[before and after 16 weeks of supplementation]

Secondary Outcome Measures

Name	Time	Method
Blood levels of: homocysteine; c-reactive protein; fibrinogen; lipids; vitamins B6, B12, C, E and folate; protein carbonyls; electrolytes.[before and after 16 weeks of supplementation]