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Clinical Trials/CTRI/2012/04/002605
CTRI/2012/04/002605
Other
未知

Randomized, Double Blind, Placebo Controlled Trial of Periappendiceal Injection of Triamcinolone in Idiopathic Ulcerative Colitis

PGIMER0 sites0 target enrollmentTBD

Overview

Phase
未知
Intervention
Not specified
Conditions
Not specified
Sponsor
PGIMER
Status
Other
Last Updated
4 years ago

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
TBD
Last Updated
4 years ago
Study Type
Interventional

Investigators

Sponsor
PGIMER

Eligibility Criteria

Inclusion Criteria

  • a.Male or female patients 18 years of age or older with an established diagnosis of IUC
  • b.In clinical remission for at least 3 months on 5\-ASA at a stable dose ranging from 1\.6 to 2\.4 g/day
  • c.Patient had achieved remission with a corticosteroid \> 20 mg/day prednisolone or an alternative medication and had successfully ceased steroid therapy
  • d.Patients undergoing colonoscopy for assessment of the extent of the disease

Exclusion Criteria

  • a.Patients on immunomodulators like azathioprine, 6 mercaptopurine and mycophenolate mofetil
  • b.Patients with severe cardiovascular diseases
  • c.Patients with laboratory abnormalities indicating anemia (hemoglobin \< 9 g/dL), leukopenia, thrombocytopenia, or abnormal coagulation;
  • d.Patients with renal or liver disease, chronic pancreatitis, diabetes mellitus, mental disorders or gallstone
  • e.Patients with infection, sepsis, or pneumonia
  • f.Pregnant or nursing women.
  • g.History of appendectomy

Outcomes

Primary Outcomes

Not specified

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