Comparing Weaning of Nasal Continuous Positive Airway Pressure (CPAP) From Preterm Infants
Not Applicable
Completed
- Conditions
- Respiratory Distress Syndrome
- Interventions
- Other: Gradual pressure wean
- Registration Number
- NCT02126501
- Lead Sponsor
- Maimonides Medical Center
- Brief Summary
To compare the 2 methods of weaning of nasal continuous positive airway pressure (CPAP) in premature babies born between 26 and 32 weeks
- Detailed Description
To study the weight and the post menstrual age (PMA) at the time of NCPAP wean utilizing the method of sudden wean as compared to gradual wean.
Methods: A prospective randomized trial was conducted comparing sudden weaning with gradual weaning from NCPAP in neonates with gestational age between 26 and 32 weeks. The patients were randomized to one of the two methods of weaning from NCPAP and their success was compared
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 70
Inclusion Criteria
- All neonates born 26 to 32 weeks of gestational age
Exclusion Criteria
- Those with severe congenital anomalies and chromosomal defects including congenital heart disease, neurological malformations, chest and airway abnormalities and lung hypoplasia
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Gradual pressure wean Gradual pressure wean NCPAP will be removed by gradually decreasing pressure over 24 hours once the weaning is decided
- Primary Outcome Measures
Name Time Method Success of weaning on first trial off NCPAP Completion of Nasal Continuous Positive Airway Pressure (NCPAP) treatment, expected average of 4 weeks
- Secondary Outcome Measures
Name Time Method Weight and corrected GA when come off oxygen when off supplemental oxygen expected average of 2 weeks Weight and corrected gestational age (GA) when neonates could come off NCPAP Completion of Nasal Continuous Positive Airway Pressure (NCPAP) treatment, expected average of 4 weeks
Trial Locations
- Locations (1)
Maimonides medcial center
🇺🇸Brooklyn, New York, United States