MedPath

Korean Post Marketing Surveillance for Comirnaty Injection (Bretovameran)

Active, not recruiting
Conditions
COVID-19 Vaccination
Interventions
Biological: Bretovameran
Registration Number
NCT06613984
Lead Sponsor
Pfizer
Brief Summary

This study is to identify any problems and questions with respect to the safety of Comirnaty Injection (Bretovameran) during the post-marketing period.

Detailed Description

All assessments are performed as part of normal clinical practice or standard practice guidelines for the subject population and healthcare provider specialty in the countries where this non-interventional study is being conducted.

This study is conducted under normal clinical practice in accordance with regulatory requirements. Therefore, the inclusion and exclusion criteria for study subjects are related to indications and contraindications outlined in the local product document. This study will not provide or make recommendations on any vaccine use. The vaccines are all given as part of the standard of care. All enrolled subjects have to meet the general prescription criteria for Comirnaty Injection (Bretovameran) according to the local product document and have to be enrolled at the doctor's discretion.

This is an open-label, non-comparative, non-interventional, prospective, and multi-center study conducted in Korean health care centers by accredited physicians (investigator). The study population is Korean subjects who are scheduled for COVID-19 vaccination. Comirnaty Injection (Bretovameran) will be administered according to the "Dosage and Administration" of the authorized label. There is no visit or activity mandated by this study. The investigator will collect data from the subject's medical records and diary and record data on each subject's case report form (CRF).

Recruitment & Eligibility

Status
ACTIVE_NOT_RECRUITING
Sex
All
Target Recruitment
660
Inclusion Criteria
  • Korean subjects who are eligible for administration of Comirnaty Injection according to the locally authorized label
  • Subjects with evidence of a personally signed and dated informed consent/assent document indicating that the subject (or a legally acceptable representative) has been informed of all pertinent aspects of the study
Exclusion Criteria
  • Subjects who involved in the contraindications of use indicated in the locally authorized label
  • Subjects with a history of hypersensitivity to any ingredients of this product or this product
  • Any subjects (or a legally acceptable representative) who does not agree that Pfizer and companies working with Pfizer use his/her information

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
BretovameranBretovameranKorean subjects who are eligible for administration of Comirnaty Injection (Bretovameran) according to the locally authorized label
Primary Outcome Measures
NameTimeMethod
Number of subjects with Solicited adverse events1 week after administration of Comirnaty Injection (Bretovameran)

Solicited adverse events within 1 week after each dose of Comirnaty Injection (Bretovameran) and the number of subjects with such events will be collected.

Number of subjects with Unsolicited adverse events28 days after administration of Comirnaty Injection (Bretovameran)

Unsolicited adverse events within 28 days after each dose of Comirnaty Injection (Bretovameran) and the number of subjects with such events will be collected.

Secondary Outcome Measures
NameTimeMethod
Number of subjects with Adverse events (AEs)28 days after administration of Comirnaty Injection (Bretovameran)

All adverse events within 28 days after each dose of Comirnaty Injection (Bretovameran) and the number of subjects with such events will be collected.

Number of subjects with Serious Adverse Events (SAEs)28 days after administration of Comirnaty Injection (Bretovameran)

All Serious adverse events within 28 days after each dose of Comirnaty Injection (Bretovameran) and the number of subjects with such events will be collected.

Number of subjects with Expected Adverse Events28 days after administration of Comirnaty Injection (Bretovameran)

All expected adverse events within 28 days after each dose of Comirnaty Injection (Bretovameran) and the number of subjects with such events will be collected.

Number of subjects with Unexpected Adverse Events28 days after administration of Comirnaty Injection (Bretovameran)

All Unexpected Adverse Events within 28 days after each dose of Comirnaty Injection (Bretovameran) and the number of subjects with such events will be collected.

Number of subjects with Adverse Drug Reactions28 days after administration of Comirnaty Injection (Bretovameran)

All Adverse Drug Reactions within 28 days after each dose of Comirnaty Injection (Bretovameran) and the number of subjects with such events will be collected.

Number of subjects with Serious Adverse Drug Reactions28 days after administration of Comirnaty Injection (Bretovameran)

All Serious Adverse Drug Reactions within 28 days after each dose of Comirnaty Injection (Bretovameran) and the number of subjects with such events will be collected.

Number of subjects with Expected Adverse Drug Reactions28 days after administration of Comirnaty Injection (Bretovameran)

All Expected Adverse Drug Reactions within 28 days after each dose of Comirnaty Injection (Bretovameran) and the number of subjects with such events will be collected.

Number of subjects with Unexpected Adverse Drug Reactions28 days after administration of Comirnaty Injection (Bretovameran)

All Unexpected Adverse Drug Reactions within 28 days after each dose of Comirnaty Injection (Bretovameran) and the number of subjects with such events will be collected.

Trial Locations

Locations (1)

Pfizer Korea

🇰🇷

Seoul, Korea, Republic of

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