Impact of Different Resistance Training Protocols on Pain in Knee Osteoarthritis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 28
- 试验地点
- 1
- 主要终点
- Change in self-reported pain intensity
研究概览
简要总结
This study aim to evaluate pain after different resistance training protocols (placebo, 4 sets of 10RM, 8 sets of 10 RM and 12 sets of 10RM) in patients with severe knee osteoarthritis.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 55 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •men and women at least 55 years old
- •diagnosed with severe knee OA
- •scheduled for unilateral Total Knee Arthroplasty (TKA) surgery
排除标准
- •pain in the contralateral (non-studied) limb (maximum ≥80 of 100 mm on a visual analog scale (VAS) during daily activities)
- •another hip or knee joint replacement in the previous year
- •any medical condition in which exercise was contraindicated
- •participated in exercise programs (>2 days/week, training at intensities of 10-15RM) in the 6 months prior to the study
- •history of stroke, brain surgery, major depression, or any self-perceived cognitive alterations that could affect the performance of study tasks
结局指标
主要结局
Change in self-reported pain intensity
时间窗: Pre-exercise (pre), immediate post exercise (post), and 10 min after exercise (post 10min)
Measure of knee pain intensity with the Visual Analogue Scale (0-100mm), with higher scores reflecting higher perceived pain intensity
Change in pressure pain thresholds
时间窗: Pre-exercise (pre), immediate post exercise (post), and 10 min after exercise (post 10min)
Measured with a mechanical algometer (Wagner Instruments, Greenwich, CT, USA) in three sites (vastus medialis of the affected limb, vastus medialis of the unaffected limb, and distal to the non-dominant arm lateral epicondyle)
次要结局
- WOMAC questionaire(pre-exercise)
- Tampa Scale of Kinesiophobia (TSK 11)(pre-exercise)
- Chronic Pain Self-Efficacy Scale(pre-exercise)
- Pain Catastrophizing Scale(pre-exercise)
研究者
José Casaña Granell
Head of the Physiotherapy Department
University of Valencia