Comparison of effect of Darvyadi ghee verses Darvyadi kwath in two group w.s.r.DM

Phase 2/3

Not yet recruiting

Conditions: Type 2 diabetes mellitus with other specified complications,

Registration Number: CTRI/2019/04/018366

Lead Sponsor: All India Institute of Ayurveda

Brief Summary: Diabetes mellitus comprises a group of metabolic disorder share the common phenotype of hyperglycemia. Diabetes mellitus is a syndrome of impaired carbohydrate, fat and protein metabolism Acharya Charaka, has classified Prameha into two types, i.e. Sthula Pramehiviii and Krisha Pramehi .

Kaphaja and Pittaja Pramehas persisting for long time may present with predominance of Vata dosha, producing the features of vata pradhana prameha associated with dhatukshaya lakshanas. in case of Vatapradhana prameha where acharyas have suggested the drugs in the form of Ghritas prepared out of the drugs mentioned for other type of pramehas so that atikarshana should not aggreviate vata and in turn no results by the treatment or worsening of the condition may be seen. With this approach the Darvyadi ghrita is taken prepared out of the Kashaya drugs mentioned for all types of Prameha which will alleviate Kapha and pitta dosha aslo will take care so that vata prakopa should not occur and also alleviates it, resulting in remission of the condition.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 60

Inclusion Criteria

1 BMI < 25 2 Significant weight loss.(Loss of 4.5 kg or >5% of the usual body weight over a period of 6-12 month especially when progressive) 3 Fasting blood glucose â€“ (126-250mg/dl) 4 PPBS (200-400 mg/dl).

Exclusion Criteria

IDDM patients FBS> 250mg/dl PPBS> 400mg/dl Gestational diabetes.
Patients on steroids.
Malignant and accelerated Hypertension.
CHD Pregnant women.
Lactating mother Any other conditions interfering with the treatment of the condition.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare the efficacy of Darvyadi Ghrita and Darvyadi Kashaya by oral medication in vata pradhan Prameha with reference to subjects suffering from Diabetes Mellitus.	one year one month
Urine analysis: fasting and PP sugar	one year one month
Decrease in vataja lakshna like krish, ruksh, alpashi, pipasubhrisham, parisaranshil, daurbala	one year one month
Blood sugar level -FBS and PPBS	one year one month
Glycosylated Hb â€“ (HbA1C)	one year one month

Secondary Outcome Measures

Name	Time	Method
Lipid profile	Improvement in BMI

Trial Locations

Locations (1): All India Institute of Ayurveda
🇮🇳
South, DELHI, India
All India Institute of Ayurveda
🇮🇳South, DELHI, India
Vitthal G Huddar
Principal investigator
9986697942
drvghuddar@gmail.com