Stromal Gene Expression During Pulmonary Sarcoidosis
Terminated
- Conditions
- Sarcoidosis
- Registration Number
- NCT00837668
- Lead Sponsor
- Ohio State University
- Brief Summary
to determine the genetic pathways operating at the tissue level to cause granulomatous inflammation in the lungs and lymph nodes of patients with sarcoidosis. By so doing, we hope to identify unique genetic mechanisms which will aid in the diagnosis of sarcoidosis and will help us understand the pathogenesis of this poorly understood disease.
- Detailed Description
to collect small sample of lung tissue recovered from a clinical procedure such as bronchoscopy, or a mediastinoscopy (a procedure in which a lighted instrument (mediastinoscope) is inserted through a neck incision to visually examine the structures in the top of the chest cavity and to take a sample (biopsy) of tissue.
Recruitment & Eligibility
- Status
- TERMINATED
- Sex
- All
- Target Recruitment
- 110
Inclusion Criteria
- diagnosis of sarcoidosis
Exclusion Criteria
- inability to provide consent
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To Identify Gene Expression Patterns That Specifically Correlate With Active Pulmonary Sarcoidosis. end of study
- Secondary Outcome Measures
Name Time Method To Determine if Gene Expression Patterns Correlate With The Severity of Illness Of Sarcoidosis Patients end of study
Trial Locations
- Locations (1)
The Ohio State University
🇺🇸Columbus, Ohio, United States