Effectiveness of Interpersonal Psychotherapy (IPT) for Men and Women Prisoners With Major Depression
Overview
- Phase
- Phase 3
- Intervention
- Not specified
- Conditions
- Major Depressive Disorder
- Sponsor
- Brown University
- Enrollment
- 181
- Locations
- 5
- Primary Endpoint
- Change from Baseline in Hamilton Rating Scale for Depression (HRSD) at 3 Months
- Status
- Completed
- Last Updated
- 10 years ago
Overview
Brief Summary
This study will examine the effects of a first-line treatment for major depressive disorder (MDD), interpersonal psychotherapy (IPT), among men and women prisoners.
Detailed Description
The purpose of this 3-year randomized trial is to promote uptake of evidence-based treatment in criminal justice settings by conducting a fully-powered randomized effectiveness study that collects pilot implementation data, including cost-effectiveness data. Group IPT will be compared to treatment as usual (TAU) in a sample of 90 male and 90 female prisoners with MDD from 4 institutions, allowing us to explore gender effects.
Investigators
Dr. Jennifer Johnson
Associate Professor (Research), Department of Psychiatry and Human Behavior
Brown University
Eligibility Criteria
Inclusion Criteria
- •Meet all DSM-IV criteria for primary (non-substance induced) major depressive disorder
- •Expectation of at least 6 months of incarceration at baseline interview
- •Incarcerated for at least 4 weeks
Exclusion Criteria
- •Lifetime:
- •Bipolar disorder
- •Psychotic disorder
- •Are imminently suicidal
- •Cannot understand English well enough to understand the consent form or assessment instruments when read aloud
Outcomes
Primary Outcomes
Change from Baseline in Hamilton Rating Scale for Depression (HRSD) at 3 Months
Time Frame: 3 Months from Baseline
Secondary Outcomes
- Change from Baseline in Suicidality at 6 Months(6 Months from Baseline)
- Cost-effectiveness(6 months post-baseline)
- Change from Baseline in Hamilton Rating Scale for Depression (HRSD) at 6 Months(6 Months from Baseline)
- Change from Baseline in Suicidality at 3 Months(3 Months from Baseline)
- Change from Baseline in In-Prison Functioning at 3 Months(3 Months from Baseline)
- Change from Baseline in In-Prison Functioning at 6 Months(6 Months from Baseline)