Nutritional Study of Fish Oil in Skin Quality in Healthy Women

Not Applicable

• Conditions: Skin Health
• Interventions: Dietary Supplement: Placebo; Dietary Supplement: Ceto 10

• Registration Number: NCT05128240
• Lead Sponsor: Epax Norway AS

Brief Summary

The skin acts as a barrier against the external environment and prevents water loss from the body. Aging is a natural process leading to changes in the skin and fish oil has been shown to prevent inflammation, hyperpigmentation and UV-damage. This pilot study will determine skin characteristics after intervention with north atlantic fish oil.

Detailed Description

Women will be recruited to a placebo or fish oil group and be examined at pre- and post for skin quality parameters such as wrinkles, fine lines and trans-epithelial water loss.

Study Timeline

• Study Start: 2021-08-23
• Status Verified: 2021-11
• Study First Submitted: 2021-11-04
• Study First Submitted QC: 2021-11-16
• Last Update Submitted: 2021-11-16
• Study First Posted: 2021-11-19
• Last Update Posted: 2021-11-19
• Primary Completion: 2021-12-20
• Study Completion: 2022-03-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Female
• Target Recruitment: 30

Inclusion Criteria

Healthy women in the age of 30-65

Able to follow the following dietary restriction for 4 months (4 weeks wash-out, 3 months intervention):

• Do not take omega-3 supplements
• do not take supplements containing vitamin A
• do not take supplements containing collagen
• try to avoid using skin products containing vitamin A
• do not undergo skin treatment

Exclusion Criteria

Pregnancy or breast feeding known allergy to seafood skin treatment the last 6 months planned skin treatment during the study period

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Placebo	Placebo	4x1g corn oil capsules
Ceto 10	Ceto 10	4x1g capsules containing containing broad spectrum marine oil from north atlantic fish

Primary Outcome Measures

Name	Time	Method
Determine the change in skin quality of healthy women after supplementation with fish oil compared to corn oil	3 months	Changes in quantitative analysis of facial inflammation, wrinkles and fine lines and skin texture will be performed using the VISIA Skin Analysis system. Measurements will be made at baseline and at end of supplementation period.

Secondary Outcome Measures

Name	Time	Method
Determine the change in omega-3 index (%EPA and DHA in red blood cells) after daily intake of 4g of north atlantic fish oil compared to placebo	3 months	Fatty acid profiles will be measured from blood samples using the Omega-quant test

Trial Locations

Locations (1)

Møreforsking AS; 🇳🇴 Ålesund, Norway