Randomised controlled trial comparing syndromic molecular point-of-care testing for gastrointestinal pathogens with standard clinical care, in adults presenting to secondary care with suspected infectious gastroenteritis (GastroPOC Trial)

niversity Hospital Southampton NHS Foundation Trust0 个研究点目标入组 278 人开始时间: 2017年2月21日最近更新: 2023年5月22日

适应症

试验速览

2023 Results article in https://pubmed.ncbi.nlm.nih.gov/37116527/ (added 02/05/2023)

•1. Aged 18 years or over
•2. Has the capacity to give informed, written consent and is able and willing to adhere to the study procedures
•3. A patient in Southampton General Hospital ED, AMU, ASU or inpatient ward (if admitted directly to an inpatient ward)
•4. Can be recruited to the study within a 48 hour period of first triage by ED staff OR within a 48 hour period of arrival on AMU or ASU or inpatient ward (if admitted directly to AMU/ASU to these areas)
•5. Has an acute diarrhoeal illness and/or vomiting*
•5. Has a duration of illness less of than or equal to 14 days
•*An episode of acute diarrhoea is defined as the passage of at least 3 loose stools for at least 1 day.
•(AMU = acute medical unit, ASU = acute surgical unit, ED = emergency department)

•1. Patients not fulfilling inclusion criteria
•2. A palliative approach being taken by the treating clinicians
•3. Previously included in this study and re-presenting within the last 30 days after hospital discharge
•4. Declines to give stool sample and/or rectal swab
•Involvement in other research trials is not necessarily an exclusion criterion. Concurrent, prior or subsequent enrolment in an observational study is not expected to be an exclusion criterion, except at the discretion of the principal investigator.

发起方

niversity Hospital Southampton NHS Foundation Trust