A trial to compare the quality of induction using two different premedication combinations in children with Autism Spectrum Disorder (ASD) undergoing surgery.

Phase 3

• Conditions: Children with Autism Spectrum Disorder; Having an operation; Needing premedication; Mental Health - Autistic spectrum disorders; Anaesthesiology - Anaesthetics; Surgery - Other surgery

• Registration Number: ACTRN12616001078448
• Lead Sponsor: Murdoch Children Research Institute (MCRI)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-08-10
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 114

Inclusion Criteria

Diagnosed with ASD , between the ages of 4-16 years, ASA 1 or 2, No contraindication to premedication. Any type of operation is permitted. They are scheduled to undergo surgery.

Exclusion Criteria

ASA 3 or 4, cardiac/ respiratory conditions that exclude the use of sedation, obesity with weight more than 95% for age or BMI >30 (whatever is lower), previous intolerance or allergy to either medication or formulation component, Gastrointestinal disorders that affect absorption.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Smooth or steal induction as per Almanrader Scale of 3-5. Almanrader scale is used in multiple studies before. There is no gold standard scale for induction and most studies use a 4 or 5 point scale.[Induction of anaesthesia]