Home Orthostatic Training in Chronic Fatigue Syndrome

Completed

• Conditions: Encephalitis, myelitis and encephalomyelitis; Chronic fatigue syndrome; Nervous System Diseases

• Registration Number: ISRCTN89726128
• Lead Sponsor: ewcastle upon Tyne Hospitals NHS Foundation Trust (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2009-06-22
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

1. Chronic fatigue syndrome (CFS)/myalgic encephalomyelitis (ME) patients
2. Both males and females, aged 18 years and over
3. Patients who fulfil the Fukuda diagnostic criteria
4. Patients with an autonomic phenotype, i.e., have a composite autonomic symptom scale of greater than 32.5

Exclusion Criteria

1. Inability to give informed consent
2. Patients on drugs which can affect the autonomic nervous system which cannot be discontinued safely
3. Inability to stand for up to 40 minutes due to muscular or neurological disorders, cardiac transplantation, or pregnancy

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. Study compliance. Timepoints: 1 week, 4 weeks, 6 months.<br>2. Autonomic function. Timepoints: baseline, 1 week, 4 weeks, 6 months.

Secondary Outcome Measures

Name	Time	Method
Fatigue. Timepoints: baseline, 1 week, 4 weeks, 6 months.