MedPath

Acute Pain Trajectories and Persistent Pain After Breast Cancer Surgery

Completed
Conditions
Breast Neoplasms
Registration Number
NCT02823015
Lead Sponsor
Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Brief Summary

Persistent pain after breast cancer surgery (PPBCS) is a significant clinical problem, affecting between 25 and 50% of patients. Several factors are associated with the development of PPBCS, including acute postoperative pain. The analysis of pain trajectories through mixed model modeling is an alternative to static pain measures, improving precision and providing information on the time course of pain resolution. Our aim was to investigate if the characteristics of pain trajectories during the first postoperative week are correlated with the persistence of pain 3 months after breast cancer surgery.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
Female
Target Recruitment
46
Inclusion Criteria
  • Scheduled for breast cancer surgery
  • General anesthesia
Exclusion Criteria
  • Previous breast surgery
  • Reconstructive surgery scheduled during follow-up
  • Day-surgery patients
  • Inability to understand the questionnaires

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Presence of pain 3 months after surgery, assessed with the Brief Pain Inventory questionnaire. Yes/No3 months
Secondary Outcome Measures
NameTimeMethod
Acute pain trajectories (7 days) after surgeryOne postoperative week

The pain trajectory is the vector of 7 verbal numerical pain scores (from 0 to 10) recorded in a pain diary over the first 7 postoperative days

Trial Locations

Locations (1)

Cliniques Universitaires Saint-Luc

🇧🇪

Woluwé-St-Lambert, Belgium

© Copyright 2025. All Rights Reserved by MedPath