Comparison between 0.5% Ropivacaine and in combination with Dexmedetomidine for ultrasound guided Supraclavicular brachial plexus block for upper limb surgery.

Completed

• Conditions: Medical and Surgical,

• Registration Number: CTRI/2019/01/017309
• Lead Sponsor: JLN MEDICAL COLLEGE AJMER

Brief Summary

The aim of the study is to compare anaesthetic properties of 0.5% isobaric Ropivacaine alone and in combination with Dexmedetomidine in ultrasound guided Supraclavicular Brachial Plexus Block in upper limb surgeries in the terms of:-

PRIMARY OBJECTIVES:

To assess and compare the onset, duration and highest grade of sensory block.

To assess and compare the onset, duration and highest grade of motor block.

To assess and compare the total duration of effective analgesia by visual analog scale (VAS).

To assess and compare the peri-operative sedation Score.



SECONDARY OBJECTIVES:

1. To assess and compare the quality of anaesthesia.

2. To assess and compare the hemodynamic changes if any.

3. To assess and compare the proportion of patient having adverse

effects and any other complications.

Detailed Description

Not available

Study Timeline

• Study Completion: 2018-06-15
• Study Start: 2019-01-31
• Last Update Posted: 2019-11-15

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• Age group between 15 and 65 years.
• Body weight 30 to 80 kg.
• Patients belonging to ASA (American Society of Anaesthesiologists) class-I and II.
• Patients undergoing upper limb surgeries of duration 1-2 hours in theatre with haemoglobin at least 9 gm/dl.
• Patient free from any associated acute or chronic systemic illness.

Exclusion Criteria

• Patients not willing to participate in the study.
• Uncooperative patients.
• Patient with chronic pain or on long-term analgesics.
• Any known hypersensitivity or contraindication to ropivacaine, dexmedetomidine.
• Local pathology at the site of injection or disability limiting the performance of block.
• Patients receiving beta blockers or cardiac drugs.
• History of convulsion, allergy to the drug used, bleeding disorder, severe neurological deficit, thyroid disorder.
• Patient with history of respiratory, cardiac, hepatic or renal disease (necessitating classification in ASA Class III or above).
• Patients having a history of significant neurological, psychiatric, or neuromuscular disorders.
• Pregnant, lactating mothers.
• Inadequate block necessitating institution of general anaesthesia for continuation of surgical procedure.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To assess and compare the onset, duration and highest grade of sensory block.	Duration of study is around 1 year.
To assess and compare the onset, duration and highest grade of motor block.	Duration of study is around 1 year.
To assess and compare the total duration of effective analgesia by visual analog scale (VAS).	Duration of study is around 1 year.
To assess and compare the peri-operative sedation Score.	Duration of study is around 1 year.

Secondary Outcome Measures

Name	Time	Method
To assess and compare the quality of anaesthesia.	2. To assess and compare the hemodynamic changes if any.

Trial Locations

Locations (1)

JLN MEDICAL COLLEGE, AJMER; 🇮🇳 Ajmer, RAJASTHAN, India

JLN MEDICAL COLLEGE, AJMER

🇮🇳Ajmer, RAJASTHAN, India

Dr Vikas Gupta

Principal investigator

9694941940

vickybtp@gmail.com