Etiology of Motor Developmental Delay in Children
Completed
- Conditions
- Delayed; Development, IntellectualDelayed;Development;Physical
- Registration Number
- NCT03130972
- Lead Sponsor
- Bundang CHA Hospital
- Brief Summary
This study aims to identify the etiology of children with motor developmental delay, in association with the results of magnetic resonance imaging and genetic analysis.
- Detailed Description
Results of other available assessments including Gross Motor Function Measurements and Bayley Scale of Infant Development, second edition, modified Ashworth Scale, IQ score and developmental language assessments are to be collected.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 1355
Inclusion Criteria
- clinical diagnosis of motor developmental delay
- available results of functional assessments at ages older than 18 months Functional measures include either GMFM or BSID_II
Exclusion Criteria
- single domain delay other than motor (e.g., speech delay)
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Change of Gross Motor Function Classification System from baseline at 6 months through study completion, an average of 1 year To avoid variation in each individual the exact date of evaluation for every outcome is included to estimate the exact time from birth
- Secondary Outcome Measures
Name Time Method Brain MRI findings From the date of the first documented developmental delay until the date of last documentation or date of death from any cause, whichever came first, assessed up to 100 months the first brain MRI taken after the event causative to developmental delay, read by radiology specialists
Mental quotient From the date of the first documented developmental delay until the date of last documentation or date of death from any cause, whichever came first, assessed up to 100 months BSID-II mental month estimated/actual age in month times 100