Perioperative fluid management in patients receiving cadaveric renal transplants – Effects of normal saline versus balanced infusates on the incidence of electrolyte and acid-base disturbances
- Conditions
- patients receiving cadaveric renal transplantation
- Registration Number
- EUCTR2009-018050-34-AT
- Lead Sponsor
- Medizinische Universität Wien,Univ.Klinik f.Anästhesie, Intensivmedizin und Schmerztherapie
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Recruiting
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
All patients with end-stage-renal disease admitted for cadaveric renal transplantation will be included in the study
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range
Exclusion Criteria
-Patients younger than 18 years of age
-Hyperkalemia defined as a serum potassium exceeding 5.5 mmol/L pre-operatively
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Main Objective: In this study we want to show that the choice of a balanced type fluid solution for the perioperative fluid management of patients receiving cadaveric renal transplantation results in less occurrence of intra- and postoperative hyperkalemia, and thus the need for postoperative dialysis. Additionally, we aim to determine whether the use of a balanced infusion solution leads to less occurrence of metabolic acidosis and electrolyte disorders than the use of isotonic saline;Secondary Objective: Furthermore we want to evaluate whether perioperative fluid management with balanced infusion solutions results in a higher frequency of primary graft function than with administration of isotonic saline. <br><br>;Primary end point(s): choice of a balanced type fluid solution for the perioperative fluid management of patients receiving cadaveric renal transplantation results in less occurrence of intra- and postoperative hyperkalemia, and thus the need for postoperative dialysis
- Secondary Outcome Measures
Name Time Method