The Merendino Procedure for Benign or Early Malignant Lesions of the Distal Esophagus/Gastroesophageal Junction is Feasible, Safe and Provides Good QoL
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 26
- 试验地点
- 1
- 主要终点
- Quality of Life (QoL)
研究概览
简要总结
The purpose of this study is to analyse retrospectively the early postoperative and functional outcome of patients (pts) after Merendino procedure for benign or early malignant lesions of the distal part of the esophagus or the gastroesophageal junction.
详细描述
Between 2004 and 2013, 14 pts had transhiatal resection of median 8 (6-10) cm of distal esophagus including the gastroesophageal junction. Locoregional lymphadenectomy was performed in all patients with (suspected) early adenocarcinoma. In case of vagus nerve resection, pyloromyectomy and cholecystectomy were done. A pediculated isoperistaltic jejunal segment of 15-18 cm length was interponed between esophageal stump and remaining stomach by end-to-side anastomoses. At least one postoperative contrast examination of the anastomoses was done in all pts. Quality of life was assessed by using the EORTC QLQ-OES18 survey, recording patients' general activity and condition and specific gastrointestinal symptoms.
研究设计
- 研究类型
- Observational
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •MER or CON procedure
- •informed consent
- •CON patients were matched according to diagnosis, Age and ASA score
排除标准
- •withdrawal of informed consent
- •legal incapacity
- •limitations in mental state or medical condition precluding questioning (only QoL data)
结局指标
主要结局
Quality of Life (QoL)
时间窗: up to 10 years after surgery
EORTC QLQ-C30 and QLQ-OES24 questionnaire (global health status item, functional and symptom scale items)
次要结局
- Intraoperative complications(up to 1 day after surgery)
- Postoperative complications(up to 100 days after surgery)