Acute Musculoskeletal Responses to Isometric Blood Flow Restriction Training of the Patellar Tendon in Healthy, Active Young Adults: A Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 66
- 试验地点
- 1
- 主要终点
- Change in Patellar Tendon Thickness
研究概览
简要总结
This randomized controlled trial investigated the acute musculoskeletal responses to isometric exercise with and without blood flow restriction in healthy, physically active young adults. Participants were randomly assigned to one of three groups: high-intensity isometric exercise (HI), low-intensity isometric exercise with blood flow restriction (LI-BFR), or low-intensity isometric exercise with sham blood flow restriction (LI-Sham). Ultrasound measurements of patellar tendon and vastus medialis muscle thickness were obtained before and immediately after the exercise intervention. Knee-extension maximal voluntary isometric contraction was also assessed. The study aimed to compare the acute changes in these outcomes among the three exercise conditions.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •- Healthy men and women aged 18-40 years.
排除标准
- •Current musculoskeletal injury.
- •Cardiovascular disease.
- •Inability to complete the study protocol.
- •Diagnosis of patellar tendinopathy within the previous 6 months.
- •Contraindications to blood flow restriction, including pregnancy, thrombosis, excessive varicose veins, or a prosthesis in the region to be occluded.
研究组 & 干预措施
High-Intensity Isometric Exercise (HI)
Participants performed five 30-second isometric knee-extension contractions at 70% of maximal voluntary isometric contraction (MVIC), with 60 seconds of rest between sets.
干预措施: High-Intensity Isometric Exercise (Behavioral)
Low-Intensity Isometric Exercise With Blood Flow Restriction (LI-BFR)
Participants performed five 30-second isometric knee-extension contractions at 30% of MVIC with a pneumatic cuff inflated to 80% of the individual arterial occlusion pressure (AOP) during each contraction. The cuff was deflated during the 60-second rest periods between sets.
干预措施: Low-Intensity Isometric Exercise With Blood Flow Restriction (Behavioral)
Low-Intensity Isometric Exercise With Sham Blood Flow Restriction (LI-Sham)
Participants performed five 30-second isometric knee-extension contractions at 30% of MVIC with a pneumatic cuff inflated to 20 mmHg during each contraction. The cuff was deflated during the 60-second rest periods between sets.
干预措施: Low-Intensity Isometric Exercise With Sham Blood Flow Restriction (Behavioral)
结局指标
主要结局
Change in Patellar Tendon Thickness
时间窗: Baseline and immediately post-intervention
Patellar tendon thickness was assessed by B-mode ultrasonography at 25%, 50%, and 75% of the tendon length, from the inferior pole of the patella to the tibial tuberosity.
次要结局
- Change in Vastus Medialis Muscle Thickness(Baseline and immediately post-intervention)
- Change in Knee-Extension Maximal Voluntary Isometric Contraction (MVIC)(Baseline and immediately post-intervention)
研究者
YASSER ALAKHDAR MOHMARA
Professor / Principal Investigator
University of Valencia