NCT06146309已完成不适用
Assessment Of Peri-papillary Retinal Nerve Fiber Layer Thickness In Patients With Unilateral Branch Retinal Vein Occlusion
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- peri-papillary retinal nerve fiber layer thickness
研究概览
简要总结
Several studies have indicated a relation between the development of RVO and elevated intraocular pressure (IOP) and glaucoma [9]. Further investigations into the structural alterations in the fellow eyes of individuals with unilateral RVO have revealed that the pRNFL is thinner than in healthy eyes, suggesting that there may be systemic risk factors for both RVO and glaucoma
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 47 Years 至 68 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •patients with unilateral BRVO
排除标准
- •History of retinal and/or optic nerve diseases involving glaucomatous optic disc, ischemic optic neuropathy, or optic neuritis.
- •History of trauma, intravitreal injections, vitreoretinal surgeries, and retinal or macular lasers.
- •A significant media opacity that makes it difficult to capture clear images.
- •No history of diabetes and/or hypertension in those recruited as the control group
研究组 & 干预措施
Patients with unilateral BRVO
Experimental
干预措施: aflibercept (2mg/0.05ml) (Drug)
结局指标
主要结局
peri-papillary retinal nerve fiber layer thickness
时间窗: 24 months post injection
Layer of the retina. The thickness was measured by Optical Coherence Tomography
次要结局
未报告次要终点
研究者
Akram Fekry Elgazzar
Principal Investigator
Al-Azhar University
研究点 (1)
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