Pilot study assessing the effects of poorly absorbed sugars in enteral formula on colonic gas production and symptom induction in healthy subjects

Phase 4

Completed

• Conditions: Enteral nutrition-associated diarrhoea; Oral and Gastrointestinal - Other diseases of the mouth, teeth, oesophagus, digestive system including liver and colon; Diet and Nutrition - Other diet and nutrition disorders

• Registration Number: ACTRN12613000500752
• Lead Sponsor: Department of Gastroenterology, Central Clinical School, Monash University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2013-05-07
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 34

Inclusion Criteria

Healthy subjects or subjects with functional gut symptoms such as irritable bowel syndrome over the age of 18 years

Exclusion Criteria

1.Organic disease or condition predisposing the patient to diarrhoea (e.g. inflammatory bowel disease, bowel resection, untreated coeliac disease)
2.Non-breath hydrogen producer after lactulose ingestion
3.Use of antidiarrhoeal medications for one week prior to study commencement
4.Probiotic or prebiotic use for two weeks prior to study commencement
5.Antibiotic use for two weeks prior to study commencement

Study & Design

• Study Type: Interventional
• Study Design: Not specified