Effect of Transparent, Self-drying Silicone Gel on the Treatment of Hypertrophic Abdominal Scars
Phase 4
Completed
- Conditions
- KeloidsHypertrophic Scars
- Interventions
- Other: Topical silicone gelOther: Vaseline
- Registration Number
- NCT01078428
- Lead Sponsor
- Mahidol University
- Brief Summary
Keloids and hypertrophic scars are a common subject of dermatologic consultations. Therapeutic management of such conditions remains challenging because of their high rate of recurrence and lack of curative treatment.
- Detailed Description
Silicone gel Sheeting (SGS) is one treatment modality that has proven effective for treatment of hypertrophic scar. One disadvantage of SGS is its application technique. To be effective, SGS must be applied on the scar for at least 12 hours daily. Topical silicone gel is a novel therapy that has shown promising result on scar prevention. However, the efficacy and safety of topical silicone gel for treatment of hypertrophic scar has not been confirmed.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 38
Inclusion Criteria
- subjects at least 18 years old
- subjects with hypertrophic abdominal scar
- Have not received treatment on the scar at least 1 month prior to the enrollment.
Exclusion Criteria
- subject who has previous history of silicone allergy
- subject who smoke cigarette
- subject who was treated with x-rays irradiation in the past
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Silicone gel Topical silicone gel Gel containing silicone gel Vaseline Vaseline Gel containing petrolatum gel
- Primary Outcome Measures
Name Time Method Scar thickness 1, 2 and 5 months after initiation of treatment
- Secondary Outcome Measures
Name Time Method Clinical assessment on overall scar appearance 1, 2 and 5 months after initiation of treatment
Trial Locations
- Locations (1)
Faculty of Medicine Siriraj Hospital
🇹🇭Bangkoknoi, Bangkok, Thailand