Taipei Tzu Chi Hospital,The Buddhist Medical Fundation
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- viral shedding and the decline of acute inflammation
研究概览
简要总结
Chinese herbal medicine Jing si herbal tea can effectively reduce the expression of SARS CoV2 in the throat of infected patients, provide medical discoveries, formulate effective isolation policies of hospitals and homes, count the virus retention, develop effective medical care and protection of medical personnel, and create a win-win situation.
详细描述
Background:
COVID-19 is caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2). Studies have pointed out that the traditional Chinese herbal medicine Yinqiao powder has been analyzed by network pharmacology and it may be through Interleukin-6, Mitogen-Activated Protein Kinase 3, Tumor necrosis factor and Tumor protein p53 pathways treat COVID-19 infection [1]. In addition, the clinical case report pointed out that a 38-year-old woman who currently lives in Wuhan was diagnosed by a Chinese physician and given appropriate Chinese herbal medicine. One week later, the patient's symptoms eased and her lungs CT scan showed that her lungs substantive phenomenon has reduction [2].
Aims of the study:
This study is a prospective observational study with the following three purposes.
First, cooperate with the treatment of the domestic temporary diagnosis and treatment guidelines, observe the expression level of the SARS CoV2 virus of the infected patients, and provide the research and development of effective treatment for the future.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •COVID infection patient and age over eighteen
排除标准
- •severe pneumonia needing mechanical ventilation
- •severe systemic diseases (i.e., malignancy, autoimmune diseases, liver or renal diseases)
- •women during pregnancy or lactation
- •participation in clinical trials within 3 months
- •known allergies to the investigational medications
- •other conditions judged by the investigators.
研究组 & 干预措施
Jing-Si-Herbal-Tea(JSHT)
Eligible patients were randomized to receive routine treatment alone based on the Novel Coronavirus Interim Guidelines for Clinical Management of SARS-CoV-2 Infection (Eleventh edition 2021) (control group) or the combination of routine treatment and JSHT (1 drink thrice daily for 7 days) (JSHT group) at the discretion of the attending clinicians.
干预措施: Jing-Si-Herbal-Tea (Drug)
结局指标
主要结局
viral shedding and the decline of acute inflammation
时间窗: 3 months
Reverse transcription-polymerase chain reaction Cycle threshold ratio calculation (numerical value) as rising speed and reducing amplitude of C-Reaction protein (mg/dL)
次要结局
未报告次要终点
研究者
Yao-Kuang Wu
Director of division of pulmonary and critical care care medicine
Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation