Investigating the efficacy of intracavernosal injection of platelet-rich plasma (PRP) in the treatment of erectile dysfunction in diabetic patients with oral treatments-resistent to
- Conditions
- Erectile dysfunction.N52.9Male erect
- Registration Number
- IRCT20100817004582N9
- Lead Sponsor
- Guilan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Male
- Target Recruitment
- 58
Non-responder to PDE5Is
Having score at least 21 in IIEF questionnair
More than 6 months have passed since erectile dysfunction
Have at least 10 years of diabets history
Having persistent sex in last 3 months
History of using PDE5Is in the last month
History of psychological disorders and use of related drugs for its treatment
History ofusing energy therapy for erectile dysfunction in the last month
History of radiation or penile surgery or having penile prosthesis
History of trauma, fracture and pelvic surgery
History of priapism, penile fracture and Peyronie's
History of using anti-androgen and selective serotonin reuptake inhibitors (SSRIs)
Presence of active infection evidence in the injected area
Abnormal morning testosterone levels (lower than 200 and above 1197)
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Erectile function. Timepoint: Before intervention, 1, 3 and 6 months after last injection. Method of measurement: The International Index of Erectile Dysfunction (IIEF) questionnaire.;Erection quality. Timepoint: Before intervention, 1, 3 and 6 months after last injection. Method of measurement: Erectile Hardness Score (EHS) index.
- Secondary Outcome Measures
Name Time Method Patient satisfaction score of treatment. Timepoint: 1, 3 and 6 months after last injection. Method of measurement: Erectile Dysfunction Inventory of Treatment Satisfaction (EDITS).