Efficacy of perioperative pregabalin in ankle fractures; a prospective randomized controlled trial
Not Applicable
Completed
- Conditions
- Injury, poisoning and certain other consequences of external causes
- Registration Number
- KCT0007008
- Lead Sponsor
- Catholic Kwandong University International St.Mary's Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
1. Age : from 19 years to 65 years old
2. Trauma within 3 weeks
Exclusion Criteria
1. Pilon fracture, open fracture, multiple fractures
2. Charcot's arthropathy
3. Creatinine > 1.2mg/dl, GFR < 60ml/min/1.73m2, chronic renal disease, peptic ulcer, diabetes mellitus over 5 years, coronary heart disease or myocardial infarction within 1 year
4. Spinal anesthesia, patient who declined to receive PCA
5. Patients who are taking NSAIDs, pregabalin already or who have side effects against those
6. Any surgical history on ipsilateral ankle or arthritic history on ipsilateral ankle
7. Systemic arthritis such as rheumatoid arthritis, gout arthritis
8. Any contraindication to the using drugs
9. Pregnant or breast feeding women
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method pain, Functional recovery, and bone union
- Secondary Outcome Measures
Name Time Method se, amount, and the time to first use of narcotic pain killers, any side effects of NSAIDs, pregabalin