Clinical Database for the Early Recognition of Pulmonary Parenchymal Involvement in Patients With Systemic Diseases Bearing a Risk for Interstitial Lung Disease

Medical University of Graz1 site in 1 country412 target enrollmentMay 1, 2021

ConditionsLung Diseases, Interstitial

Interventionschest CT

Overview

Phase: Not Applicable
Intervention: chest CT
Conditions: Lung Diseases, Interstitial
Sponsor: Medical University of Graz
Enrollment: 412
Locations: 1
Primary Endpoint: DLCO%pred (carbon monoxide diffusing capacity) at time of ILD diagnosis
Status: Recruiting
Last Updated: 3 months ago

Overview Investigators Eligibility Criteria Arms & Interventions Outcomes Sites Similar Trials

Overview

Brief Summary

The purpose of this study is to establish a clinical database for patients bearing at risk for ILD (Interstitial Lung Disease) and to set up a prospective ILD Screening program for these patients.

Registry

clinicaltrials.gov

Start Date

May 1, 2021

End Date

January 31, 2029

Last Updated

3 months ago

Study Type

Observational

Sex

All

Investigators

Sponsor

Medical University of Graz

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•Age: ≥ 18 years
•patients with a known systemic disease bearing a risk for ILD
•signed informed consent (for prospective part)

Exclusion Criteria

•Age \< 18 years
•comorbidities severely limiting life-expectancy (e.g. severe cardiovascular conditions, malignant disease)

Arms & Interventions

prospective patient cohort

patients who will undergo the prospective ILD Screening algorithm

Intervention: chest CT

retrospective patient cohort

patients with diagnosed ILD

Intervention: chest CT

Outcomes

Primary Outcomes

DLCO%pred (carbon monoxide diffusing capacity) at time of ILD diagnosis

Time Frame: 5 years

The investigators aim to assess DLCO% pred at time of ILD diagnosis in patients undergoing a ILD Screening algorithm and compare to the retrospective patient cohort with diagnosed ILD and the DLCO%pred at time of ILD diagnosis