临床试验/NCT05198947

NCT05198947已完成不适用

Better Disease Control by Multidrug Regimen in Scabies: A Randomized Controlled Trial

B.P. Koirala Institute of Health Sciences0 个研究点目标入组 212 人开始时间: 2017年1月最近更新: 2022年1月20日

适应症

干预措施

试验速览

阶段: 不适用
状态: 已完成
发起方: B.P. Koirala Institute of Health Sciences
入组人数: 212
主要终点: Pruritus

研究概览研究设计入排标准研究组 & 干预措施结局指标研究者记录与标识符相似试验

研究概览

简要总结

Scabies is associated with significant discomfort and social taboo. Existing treatment regimen frequently fails due to lack of patient compliance. We compared single use regimen to existing standard repeat application regimen for treatment of scabies.

研究设计

研究类型: Interventional
分配方式: Randomized
干预模型: Parallel
主要目的: Treatment
盲法: Single (Outcomes Assessor)

入排标准

年龄范围: 5 Years 至 80 Years（Child, Adult, Older Adult）
性别: All
接受健康志愿者: 否

入选标准

•Willing patients
•Clinical diagnosis of scabies
•Within the age limits

排除标准

•Unwilling patients
•Patients with severe co-morbidities requiring long term medication
•Pregnant women
•Patients who don't fulfill the age limit criteria

研究组 & 干预措施

Group 1 Permethrin only

Active Comparator

Standard regimen of permethrin 5% topical application to be repeated after 1 week.

干预措施: Permethrin Lotion 5% (Drug)

Group 2 Permethrin and Ivermectin

Active Comparator

A combination regimen of permethrin 5% topical application with oral ivermectin 200 mcg/kg given on the single day only

干预措施: Permethrin Lotion 5% and Oral Ivermectin 200 mcg/kg (Drug)

结局指标

主要结局

Pruritus

时间窗: 1 month

Rate of relief from pruritus assessed using visual analog scale

次要结局

Skin lesions(1 month)

研究者

发起方

B.P. Koirala Institute of Health Sciences

申办方类型

Other

责任方

Principal Investigator

主要研究者

Prajwal Pandey

Assistant Professor

B.P. Koirala Institute of Health Sciences

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