Early or late intervention in high risk non-ST elevation acute coronary syndromes

Completed

• Conditions: on ST-Elevation Acute Coronary Syndrome (NSTE-ACS); Circulatory System; Coronary diseases

• Registration Number: ISRCTN39230163
• Lead Sponsor: Isala Clinics (Isala klinieken) (Netherlands)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2006-11-22
• Last Update Posted: 9 January 2017

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 540

Inclusion Criteria

Ischemic Chest Pain or Dyspnoe at rest with last attack less than 24 hours with at least two out of three of the following characteristics:
1. Evidence of extensive myocardial ischemia on ElectroCardioGram (ECG): (new) cumulative ST depression more than 5 mm or temporary ST segment elevation in two contiguous leads less than 30 minutes
2. Evidence of myocardial damage: positive troponin (more than 0.05 ng/ml) or myoglobin (more than 150 microg/l) on admission or three hours later or positive CKmb fraction on admission (more than 6% of total CK)
3. Age above 65 years

Exclusion Criteria

1. Persistent ST segment elevation
2. Absolute contra-indication for diagnostic angiography
3. Active bleeding
4. Cardiogenic shock
5. Acute posterior infarction
6. Life expectancy less than one year

Study & Design

• Study Type: Interventional
• Study Design: Not specified