A Study to compare two ways of deciding when to give blood transfusions during liver transplant to recipient which tests if Thromboelastography(Test 1) or Rotational thromboelastometry (Test 2)is better and the total amount of blood transfused between two groups will be compared.
Phase 2
- Conditions
- Health Condition 1: K746- Other and unspecified cirrhosis ofliver
- Registration Number
- CTRI/2024/05/066783
- Lead Sponsor
- Institute Of Liver and Biliary Sciences (ILBS)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
All adult patients undergoing living donor liver transplant at our institute.
Exclusion Criteria
1)Acute liver failure patients, Acute on chronic liver failure patients
2) Pediatric patients
3)Retransplantation in a patient previously randomized in this trial
4) Without informed consent
5) Patients with known coagulation factor deficiencies.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Total PRBCs transfused between two groups.Timepoint: Baseline, dissection phase, anhepatic phase, post reperfusion and postoperative day 1 ,2 and 3
- Secondary Outcome Measures
Name Time Method 1 To compare the amount of FFP,Cryoprecipitate & platelets transfused between both groups <br/ ><br>2.To compare the changes in coagulation during different stages of liver transplant between the two groups <br/ ><br>3. To compare the duration of mechanical ventilationTimepoint: Baseline <br/ ><br>Dissection phase <br/ ><br>Anhepatic phase <br/ ><br>Post reperfusion <br/ ><br>Postoperative day 1, 2 & 3 <br/ ><br> <br/ ><br>