Diagnostic accuracy of an AI based screening system for detection of pulmonary tuberculosis using cough sounds and symptoms
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 1,260
- 试验地点
- 1
- 主要终点
- To evaluate the sensitivity, specificity, and accuracy of the AI solution in the detection of patients with TB, using cough sounds, comorbidity and symptom history
研究概览
简要总结
This study aims to evaluate the diagnostic accuracy of an artificial intelligence (AI)-based screening system designed for the detection of pulmonary tuberculosis (TB) using cough sounds and related symptoms. TB remains a significant global health challenge, with 10.6 million new cases and 1.3 million deaths annually. Traditional diagnostic methods like microbiological tests and chest X-rays, though effective, are resource-intensive and often inaccessible in low-resource settings. This has led to significant gaps in the detection and treatment of TB, particularly in rural areas. The AI model developed in this study uses cough sounds—a prominent symptom of TB—and additional symptoms such as fever, weight loss, and night sweats to provide a cost-effective and non-invasive diagnostic tool. The AI-powered mobile application offers rapid, point-of-care screening and can be utilized by frontline healthcare workers, enabling early diagnosis even in resource-limited environments. This technology addresses the need for accessible TB screening, aiming to bridge the gap between diagnosed and undiagnosed cases.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 99.00 Year(s)(—)
- 性别
- All
入选标准
- •Age greater than 18 years Cough of any duration Willing to give consent.
排除标准
- •Individuals less than 18 years of age Patients unwilling to give consent Patients requiring emergency management (clinically unstable) Pregnant women, patients with pacemakers etc.
- •among whom X-ray is prohibited Patients currently on antitubercular therapy.
结局指标
主要结局
To evaluate the sensitivity, specificity, and accuracy of the AI solution in the detection of patients with TB, using cough sounds, comorbidity and symptom history
时间窗: at 6 months and at 12 months (or till 126 confirmed TB positive patients are found; whichever is earlier)
次要结局
未报告次要终点
研究者
Dr Neeraj Nischal
Dept. of Medicine, AIIMS, New Delhi
